RENAL-FAILURE DUE TO SULFADIAZINE IN AIDS PATIENTS WITH CEREBRAL TOXOPLASMOSIS

被引：7

作者：

FARINAS, MC

ECHEVARRIA, S

SAMPEDRO, I

GONZALEZ, A

DELMOLINO, AP

GONZALEZMACIAS, J

机构：

[1] HOSP UNIV MARQUES VALDECILLA,DEPT INTERNAL MED,SANTANDER,SPAIN

[2] HOSP UNIV MARQUES VALDECILLA,DIV BIOCHEM,SANTANDER,SPAIN

来源：

JOURNAL OF INTERNAL MEDICINE | 1993年 / 233卷 / 04期

关键词：

AIDS; CRYSTALLURIA; SULFADIAZINE;

D O I：

10.1111/j.1365-2796.1993.tb00685.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Cerebral toxoplasmosis is optimally treated with the combination of high doses of sulphadiazine and pyrimethamine. We described two patients with AIDS treated for cerebral toxoplasmosis who developed renal failure due to sulphadiazine-induced crystalluria. Symptoms and renal failure were rapidly reversed with urine alkalinization and hydration. A careful monitoring and adequate hydration of patients with AIDS treated with high doses of sulphadiazine appears mandatory to avoid this complication.

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收藏

页码：365 / 367

页数：3

相关论文

共 14 条

[1] SULFAMETHOXAZOLE, HYPOALBUMINEMIA, CRYSTALLURIA, AND RENAL-FAILURE [J].

BUCHANAN, N .

BRITISH MEDICAL JOURNAL, 1978, 2 (6131) :172-172

[2] SULFADIAZINE-ASSOCIATED OBSTRUCTIVE NEPHROPATHY OCCURRING IN A PATIENT WITH THE ACQUIRED IMMUNODEFICIENCY SYNDROME [J].

CARBONE, LG ;

BENDIXEN, B ;

APPEL, GB .

AMERICAN JOURNAL OF KIDNEY DISEASES, 1988, 12 (01) :72-75

[3] ACUTE-RENAL-FAILURE DUE TO SULFADIAZINE IN PATIENTS WITH AIDS [J].

CHRISTIN, S ;

BAUMELOU, A ;

BAHRI, S ;

BENHMIDA, M ;

DERAY, G ;

JACOBS, C .

NEPHRON, 1990, 55 (02) :233-234

[4] ACUTE RENAL-FAILURE AND HYPOGLYCEMIA DUE TO SULFADIAZINE POISONING [J].

CRAFT, AW ;

BROCKLEBANK, JT ;

JACKSON, RH .

POSTGRADUATE MEDICAL JOURNAL, 1977, 53 (616) :103-104

[5] ACQUIRED-IMMUNODEFICIENCY-SYNDROME (AIDS) AND SULFADIAZINE-ASSOCIATED ACUTE-RENAL-FAILURE [J].

GOADSBY, PJ ;

DONAGHY, AJ ;

LLOYD, AR ;

WAKEFIELD, D .

ANNALS OF INTERNAL MEDICINE, 1987, 107 (05) :783-784

[6]

JECK HS, 1943, UROLOGY, V49, P290

[7] TREATMENT OF CENTRAL NERVOUS-SYSTEM TOXOPLASMOSIS WITH PYRIMETHAMINE SULFADIAZINE COMBINATION IN 35 PATIENTS WITH THE ACQUIRED IMMUNODEFICIENCY SYNDROME - EFFICACY OF LONG-TERM CONTINUOUS THERAPY [J].

LEPORT, C ;

RAFFI, F ;

MATHERON, S ;

KATLAMA, C ;

REGNIER, B ;

SAIMOT, AG ;

MARCHE, C ;

VEDRENNE, C ;

VILDE, JL .

AMERICAN JOURNAL OF MEDICINE, 1988, 84 (01) :94-100

[8] NEUROLOGICAL MANIFESTATIONS OF THE ACQUIRED IMMUNODEFICIENCY SYNDROME (AIDS) - EXPERIENCE AT UCSF AND REVIEW OF THE LITERATURE [J].

LEVY, RM ;

BREDESEN, DE ;

ROSENBLUM, ML .

JOURNAL OF NEUROSURGERY, 1985, 62 (04) :475-495

[9] TOXOPLASMIC ENCEPHALITIS [J].

LUFT, BJ ;

REMINGTON, JS .

JOURNAL OF INFECTIOUS DISEASES, 1988, 157 (01) :1-6

[10] SULFADIAZINE-INDUCED CRYSTALLURIA IN AIDS PATIENTS WITH TOXOPLASMA ENCEPHALITIS [J].

MOLINA, JM ;

BELENFANT, X ;

DOCOLECOMPTE, T ;

IDATTE, JM ;

MODAI, J .

AIDS, 1991, 5 (05) :587-589