CONTINUOUS, LOW-DOSE THERAPY WITH INTERFERON-ALPHA FOR HUMAN-IMMUNODEFICIENCY-VIRUS (HIV)-RELATED IMMUNE THROMBOCYTOPENIC PURPURA

被引：6
作者：
NORTHFELT, DW
KAPLAN, LD
ABRAMS, DI
机构：
[1] AIDS/Oncology Division, San Francisco General Hospital, University of California, San Francisco
来源：
AMERICAN JOURNAL OF HEMATOLOGY | 1991年 / 38卷 / 03期
关键词：
PLATELET COUNT; HIV-ITP; IMMUNOSUPPRESSIVE;
D O I：
10.1002/ajh.2830380317
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A patient with HIV-related immune thrombocytopenic purpura (HIV-ITP) had a rapid rise in platelet count when treated with interferon-alpha-2b, 3 million units three times weekly. There were no significant toxicities with therapy. His platelet count fell to pretreatment levels when therapy was discontinued, then increased again when therapy was reinstituted at 1.5 million units three times weekly. Interferon-alpha-2b, administered continuously at low doses, is well tolerated, effective, and possibly less immunosuppressive than other treatments for HIV-ITP.
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收藏
页码：238 / 239
页数：2
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