CELL-GROWTH ON IMMOBILIZED CELL-GROWTH FACTOR .6. ENHANCEMENT OF FIBROBLAST CELL-GROWTH BY IMMOBILIZED INSULIN AND OR FIBRONECTIN

被引：47

作者：

ITO, Y ^{[1
]}

INOUE, M ^{[1
]}

LIU, SQ ^{[1
]}

IMANISHI, Y ^{[1
]}

机构：

[1] KYOTO UNIV,FAC ENGN,DEPT POLYMER CHEM,SAKYO KU,KYOTO 60601,JAPAN

来源：

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH | 1993年 / 27卷 / 07期

关键词：

D O I：

10.1002/jbm.820270709

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

A cell growth factor protein (insulin) and/or a cell-adhesion protein (fibronectin) were immobilized on surface-hydrolyzed poly(methyl methacrylate) membranes. The growth of mouse fibroblast cells STO was accelerated by the immobilized insulin. This acceleration was enhanced by introduction of spacer arms. Coimmobilization of insulin and fibronectin was very effective for the acceleration of cell growth.

引用

页码：901 / 907

页数：7

共 21 条

[1] STRUCTURE OF RHOMBOHEDRAL 2 ZINC INSULIN CRYSTALS [J].

ADAMS, MJ ;

BLUNDELL, TL ;

DODSON, EJ ;

DODSON, GG ;

VIJAYAN, M ;

BAKER, EN ;

HARDING, MM ;

HODGKIN, DC ;

RIMMER, B ;

SHEAT, S .

NATURE, 1969, 224 (5218) :491-&

[2] ANIMAL-CELL SHAPE CHANGES AND GENE-EXPRESSION [J].

BENZEEV, A .

BIOESSAYS, 1991, 13 (05) :207-212

[3]

BRADFORD MM, 1976, ANAL BIOCHEM, V72, P248, DOI 10.1016/0003-2697(76)90527-3

[4]

CUATRECASAS P, 1973, FED PROC, V32, P1838

[5]

GORDEN P, 1980, DIABETOLOGIA, V18, P263

[6] DESIGN AND SYNTHESIS OF BIOCOMPATIBLE POLYMERIC MATERIALS [J].

IMANISHI, Y ;

ITO, Y ;

LIU, LS ;

KAJIHARA, M .

JOURNAL OF MACROMOLECULAR SCIENCE-CHEMISTRY, 1988, A25 (5-7) :555-570

[7] CELL-GROWTH ON IMMOBILIZED CELL-GROWTH FACTOR .2. ADHESION AND GROWTH OF FIBROBLAST CELLS ON POLY(METHYL METHACRYLATE) MEMBRANE IMMOBILIZED WITH PROTEINS OF VARIOUS KINDS [J].

ITO, Y ;

LIU, SQ ;

NAKABAYASHI, M ;

IMANISHI, Y .

BIOMATERIALS, 1992, 13 (11) :789-794

[8] MATERIALS FOR ENHANCING CELL-ADHESION BY IMMOBILIZATION OF CELL-ADHESIVE PEPTIDE [J].

ITO, Y ;

KAJIHARA, M ;

IMANISHI, Y .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1991, 25 (11) :1325-1337

[9] SYNTHESIS AND ANTITHROMBOGENICITY OF ANIONIC POLYURETHANES AND HEPARIN-BOUND POLYURETHANES [J].

ITO, Y ;

SISIDO, M ;

IMANISHI, Y .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1986, 20 (08) :1157-1177

[10]

ITO Y, 1990, Artificial Organs, V14, P304

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