Prevalence of Hyposalivation in Patients with Systemic Lupus Erythematosus in a Brazilian Subpopulation

被引：9

作者：

Leite, Cristhiane Almeida ^{[1
,2
]}

Galera, Marcial Francis ^{[3
]}

Espinosa, Mariano Martinez ^{[4
]}

Teles de Lima, Paulo Ricardo ^{[5
]}

Fernandes, Vander ^{[6
]}

Borges, Alvaro Henrique ^{[7
]}

Dias, Eliane Pedra ^{[2
]}

机构：

[1] Univ Cuiaba, Dept Oral Pathol, Ave Manoel Jos Arruda 3-100 Jardim Europa, BR-78065900 Cuiaba, MT, Brazil

[2] Fed Fluminense Univ, Dept Pathol, BR-033900 Niteroi, RJ, Brazil

[3] Univ Fed Mato Grosso, Sch Med, Dept Pediat, BR-78060900 Cuiaba, RJ, Brazil

[4] Univ Fed Mato Grosso, Inst Exact Sci, Dept Stat, BR-78060900 Cuiaba, RJ, Brazil

[5] Univ Cuiaba, Sch Dent, BR-78065900 Cuiaba, RJ, Brazil

[6] Univ Cuiaba, Dept Rheumatol, BR-78065900 Cuiaba, RJ, Brazil

[7] Univ Cuiaba, Fac Dent, BR-78065900 Cuiaba, RJ, Brazil

来源：

INTERNATIONAL JOURNAL OF RHEUMATOLOGY | 2015年 / 2015卷

关键词：

D O I：

10.1155/2015/730285

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background. Systemic lupus erythematosus (SLE) is a chronic inflammatory, multisystem, and autoimmune disease. Objective. The aim of this study was to describe the prevalence of hyposalivation in SLE patients and evaluate factors associated. Methods. This is a cross-sectional study developed at the Cuiaba University General Hospital (UNIC-HGU), Mato Grosso, Brazil. The study population consisted of female SLE patients treated at this hospital from06/2010 to 12/2012. Unstimulated salivary flow rates (SFRs) were measured. Descriptive and inferential analyses were performed in all cases using a significance level.. <0.05. Results. The results showed that 79% of patients with systemic lupus erythematosus suffered from hyposalivation and that the disease activity and age in years were the factors that resulted in statistically significant differences. Conclusion. The activity of the disease, age >27 years, and the drugs used were factors associated with hyposalivation, resulting in a statistically significant decrease in saliva production.

引用

页数：6

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