NEUTROPHIL APOPTOSIS AND CLEARANCE FROM NEONATAL LUNGS

被引：187

作者：

GRIGG, JM

SAVILL, JS

SARRAF, C

HASLETT, C

SILVERMAN, M

机构：

[1] HAMMERSMITH HOSP,ROYAL POSTGRAD MED SCH,DEPT MED,LONDON W12 0HS,ENGLAND

[2] HAMMERSMITH HOSP,ROYAL POSTGRAD MED SCH,DEPT HISTOPATHOL,LONDON W12 0HS,ENGLAND

[3] CITY HOSP EDINBURGH,DEPT RESP MED,EDINBURGH EH10 5SB,MIDLOTHIAN,SCOTLAND

来源：

LANCET | 1991年 / 338卷 / 8769期

关键词：

D O I：

10.1016/0140-6736(91)91443-X

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

8 newborn babies with airways inflammation, who were mechanically ventilated, underwent bronchoalveolar lavage to examine the fate of neutrophils in the inflamed airways. Light microscopy and electronmicroscopy showed evidence of neutrophil apoptosis and ingestion of intact neutrophils by macrophages in specimens from all 8 infants. Neutrophil apoptosis, without the local release of intracellular contents that promote inflammation, might represent a mechanism by which tissue injury is reduced during the resolution of neonatal pulmonary inflammation.

引用

页码：720 / 722

页数：3

共 10 条

[1] THE NEUTROPHIL [J].