ENANTIOSELECTIVE MICHAEL-TYPE REACTION OF CHIRAL LINEAR ALPHA,ALPHA-DISUBSTITUTED SECONDARY ENAMINES

被引：14
作者：
FELK, A
REVIAL, G
VIOSSAT, B
LEMOINE, P
PFAU, M
机构：
[1] ECOLE SUPER PHYS & CHIM IND VILLE PARIS,CNRS,UA 476,CHIM ORGAN LAB,F-75231 PARIS 05,FRANCE
[2] UNIV PARIS 05,PHYS LAB,F-75270 PARIS 06,FRANCE
来源：
TETRAHEDRON-ASYMMETRY | 1994年 / 5卷 / 08期
关键词：
D O I：
10.1016/0957-4166(94)80112-6
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
The enantioselective Michael-type reaction of chiral 2-substituted cyclic imines, reacting as their secondary enamine tautomers, has been extended to a linear ketimine possessing an oxo group on one of the substituents. A single secondary enamine tautomer is observed due to H-bonding of the NH group, thus allowing the reaction to proceed with a high degree of stereoselectivity.
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页码：1459 / 1462
页数：4
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