BIOACTIVATION OF N-NITROSOPIPERIDINE TO MUTAGENS - ROLE OF HEPATIC CYTOCHROME-P-450 PROTEINS AND CONTRIBUTION OF CYTOSOLIC FRACTION

被引:16
作者
AYRTON, AD [1 ]
SMITH, JN [1 ]
IOANNIDES, C [1 ]
机构
[1] UNIV SURREY,DEPT BIOCHEM,GUILDFORD GU2 5XH,SURREY,ENGLAND
关键词
D O I
10.1093/carcin/8.11.1691
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:1691 / 1695
页数:5
相关论文
共 39 条
[1]   METABOLIC-ACTIVATION OF 2-AMINO-3-METHYLIMIDAZO(4,5-F)QUINOLINE BY HEPATIC PREPARATIONS - CONTRIBUTION OF THE CYTOSOLIC FRACTION AND ITS SIGNIFICANCE TO STRAIN DIFFERENCES [J].
ABUSHAKRA, A ;
IOANNIDES, C ;
WALKER, R .
MUTAGENESIS, 1986, 1 (05) :367-370
[2]   DENITROZATION OF N-NITROSOMORPHOLINE BY LIVER-MICROSOMES - POSSIBLE ROLE OF CYTOCHROME-P-450 [J].
APPEL, KE ;
SCHRENK, D ;
SCHWARZ, M ;
MAHR, B ;
KUNZ, W .
CANCER LETTERS, 1980, 9 (01) :13-20
[3]  
BALDWIN JE, 1976, TETRAHEDRON LETT, V5, P333
[4]   ORGANOTROPE CARCINOGENE WIRKUNGEN BEI 65 VERSCHIEDENEN N-NITROSO-VERBINDUNGEN AN BD-RATTEN [J].
DRUCKREY, H ;
PREUSSMA.R ;
IVANKOVI.S ;
SCHMAHL, D ;
AFKHAM, J ;
BLUM, G ;
MENNEL, HD ;
MULLER, M ;
PETROPOU.P ;
SCHNEIDE.H .
ZEITSCHRIFT FUR KREBSFORSCHUNG, 1967, 69 (02) :103-&
[5]   MULTIPLE CYTOCHROMES-P-450 ARE TRANSLATED FROM MULTIPLE MESSENGER RIBONUCLEIC-ACIDS [J].
FAGAN, J ;
PASTEWKA, J ;
GUENGERICH, F ;
GELBOIN, H .
BIOCHEMISTRY, 1983, 22 (08) :1927-1934
[6]   MUTAGENESIS IN SALMONELLA AFTER NADH-DEPENDENT MICROSOMAL ACTIVATION OF DIMETHYLNITROSAMINE [J].
FONG, LYY ;
LEE, KM ;
LIN, HJ .
MUTATION RESEARCH, 1982, 105 (1-2) :29-36
[7]   APPARENT ACTIVATION OF 2-ACETYLAMINOFLUORENE AND SOME AROMATIC-AMINES BY CYTOSOLIC PREPARATIONS [J].
FORSTER, R ;
GREEN, MHL ;
PRIESTLEY, A ;
GORROD, JW .
MUTATION RESEARCH, 1981, 85 (04) :187-194
[8]  
GARCIA H, 1973, Z KREBSFORSCH KLIN O, V79, P141
[9]  
GILBERT PJ, 1979, TOXICOLOGY, V22, P345
[10]   MUTAGENICITY TESTING WITH SALMONELLA MICROSOME TEST [J].
GREIM, H ;
GOGGELMANN, W ;
SUMMER, KH ;
WOLFF, T .
ARCHIVES OF TOXICOLOGY, 1980, 46 (1-2) :31-40