EFFECT OF FORMULATION COMPONENTS ON DRUG-RELEASE FROM MULTIPARTICULATES

被引：17
|
作者：
NESBITT, RU
机构：
[1] Parke-Davis Pharmaceutical Research Division, Warner-Lambert Company, Morris Plains, NJ, 07950
来源：
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY | 1994年 / 20卷 / 20期
关键词：
D O I：
10.3109/03639049409041974
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The effect of excipients on the release of drug from multiparticulates or pellets coated and uncoated prepared by the extrusion/spheronization and centrifugal processes is reviewed in this paper. A processing viewpoint has been taken because of the relationship between a rugged scaleable process and reliable excipients. Only aqueous coating dispersions have been reviewed because of their increasing usage due to environmental and cost reduction programs.
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页码：3207 / 3236
页数：30
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