GAMMA-PROBE-GUIDED LYMPH-NODE LOCALIZATION IN MALIGNANT-MELANOMA

被引：277

作者：

ALEX, JC ^{[1
]}

WEAVER, DL ^{[1
]}

FAIRBANK, JT ^{[1
]}

RANKIN, BS ^{[1
]}

KRAG, DN ^{[1
]}

机构：

[1] UNIV VERMONT,COLL MED,DEPT SURG,GIVEN BLDG E309,BURLINGTON,VT 05405

来源：

SURGICAL ONCOLOGY-OXFORD | 1993年 / 2卷 / 05期

关键词：

GAMMA-PROBE; LYMPH NODE; MELANOMA; METASTASIS; TECHNETIUM;

D O I：

10.1016/S0960-7404(06)80006-X

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The initial draining lymph node (sentinel node) has been successfully localized using intraoperative vital dye mapping and reportedly is predictive of regional nodal metastases in Clinical Stage 1 melanoma [1]. In an animal model, we previously established the technique of gamma-probe-guided localization of the technetium-99 sulfur colloid labelled sentinel node [2] and found its sensitivity equal to vital dye mapping. We now report our initial experience using gamma-probe-guided localization to identify and then surgically remove the first draining lymph node(s) in 10 malignant melanoma patients. Lymphoscintigraphy was used to confirm localization. We conclude that this technique: (a) reliably localizes the sentinel node draining the site of a primary melanoma, (b) allows the lymphatic bed to be checked intraoperatively verifying complete sentinel node biopsy, and (c) is relatively simple and can be performed under local anaesthesia.

引用

页码：303 / 308

页数：6

共 34 条

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