GAMMA-PROBE-GUIDED LYMPH-NODE LOCALIZATION IN MALIGNANT-MELANOMA

被引：274
作者：
ALEX, JC [1 ]
WEAVER, DL [1 ]
FAIRBANK, JT [1 ]
RANKIN, BS [1 ]
KRAG, DN [1 ]
机构：
[1] UNIV VERMONT,COLL MED,DEPT SURG,GIVEN BLDG E309,BURLINGTON,VT 05405
来源：
SURGICAL ONCOLOGY-OXFORD | 1993年 / 2卷 / 05期
关键词：
GAMMA-PROBE; LYMPH NODE; MELANOMA; METASTASIS; TECHNETIUM;
D O I：
10.1016/S0960-7404(06)80006-X
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The initial draining lymph node (sentinel node) has been successfully localized using intraoperative vital dye mapping and reportedly is predictive of regional nodal metastases in Clinical Stage 1 melanoma [1]. In an animal model, we previously established the technique of gamma-probe-guided localization of the technetium-99 sulfur colloid labelled sentinel node [2] and found its sensitivity equal to vital dye mapping. We now report our initial experience using gamma-probe-guided localization to identify and then surgically remove the first draining lymph node(s) in 10 malignant melanoma patients. Lymphoscintigraphy was used to confirm localization. We conclude that this technique: (a) reliably localizes the sentinel node draining the site of a primary melanoma, (b) allows the lymphatic bed to be checked intraoperatively verifying complete sentinel node biopsy, and (c) is relatively simple and can be performed under local anaesthesia.
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收藏
页码：303 / 308
页数：6
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