CIRCADIAN-RHYTHMS OF MELATONIN, CORTISOL AND PROLACTIN IN PATIENTS WITH OBSESSIVE-COMPULSIVE DISORDER

被引：62
作者：
MONTELEONE, P
CATAPANO, F
DELBUONO, G
MAJ, M
机构：
[1] Institute of Psychiatry, First Medical School, University of Naples
来源：
ACTA PSYCHIATRICA SCANDINAVICA | 1994年 / 89卷 / 06期
关键词：
CIRCADIAN RHYTHM; CORTISOL; MELATONIN; OBSESSIVE-COMPULSIVE DISORDER; PROLACTIN;
D O I：
10.1111/j.1600-0447.1994.tb01538.x
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Plasma melatonin, cortisol and prolactin (PRL) levels were measured over a 24-h period in 13 drug-free patients with obsessive-compulsive disorder and in matched healthy subjects. The circadian profiles of melatonin and PRL were altered in patients; the circadian rhythm of cortisol was preserved, although at a higher level compared with normal controls. These changes were significantly related to the severity of the obsessive-compulsive symptoms. Further studies need to clarify the state- or trait-dependent character of these abnormalities.
引用
收藏
页码：411 / 415
页数：5
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