ANTISERA TO PROSTAGLANDINS - PRODUCTION AND CHARACTERIZATION

被引：10

作者：

BAUMINGER, S ^{[1
]}

机构：

[1] WEIZMANN INST SCI, DEPT HORMONE RES, REHOVOT, ISRAEL

来源：

JOURNAL OF IMMUNOLOGICAL METHODS | 1976年 / 13卷 / 3-4期

关键词：

D O I：

10.1016/0022-1759(76)90072-7

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Antisera to prostaglandins (PG) of the A, B, E and F groups were elicited by immunization with PG protein conjugates. Antibodies to PG of the A and B groups cross-react with each other, but discriminate these 2 groups of PG from those of the E and F groups. Antibodies to PG of the E groups, elicited with PG E-bovine serum albumin (PGE-BSA) conjugates in rabbits, cross-react with PG of the A and B groups. This cross-reaction is diminished by immunization of rats or mice with PGE-BSA, or by immunization of rabbits with PGE conjugated to to .gamma.-globulin or thyroblobulin. Antibodies to PGF have a marked group specificity and discriminate between this group of PG and PG of the A, B and E groups. All the antibodies produced do not discriminate between individual PG within the group.

引用

页码：253 / 259

页数：7

共 22 条

[1] RADIOIMMUNOLOGICAL ASSAY OF PROSTAGLANDIN SYNTHETASE-ACTIVITY [J].