SYNTHESIS OF [6-H-3]-1-ALPHA-HYDROXYVITAMIN-D3 AND ITS METABOLISM INVIVO TO [H-3]-1-ALPHA,25-DIHYDROXYVITAMIN-D3

被引：48

作者：

HOLICK, MF ^{[1
]}

HOLICK, SA ^{[1
]}

TAVELA, T ^{[1
]}

GALLAGHER, B ^{[1
]}

SCHNOES, HK ^{[1
]}

DELUCA, HF ^{[1
]}

机构：

[1] UNIV WISCONSIN,COLL AGR & LIFE SCI,DEPT BIOCHEM,MADISON,WI 53706

来源：

SCIENCE | 1975年 / 190卷 / 4214期

关键词：

D O I：

10.1126/science.1188356

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：576 / 578

页数：3

共 19 条

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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1973, 95 (08) :2748-2749

[2] ACTION OF 1,25-DIHYDROXYCHOLECALCIFEROL, A POTENT, KIDNEY-PRODUCED METABOLITE OF VITAMIN-D3, IN UREMIC MAN [J].

BRICKMAN, AS ;

NORMAN, AW ;

COBURN, JW .

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[3] UNIQUE BIOSYNTHESIS BY KIDNEY OF A BIOLOGICALLY ACTIVE VITAMIN-D METABOLITE [J].

FRASER, DR ;

KODICEK, E .

NATURE, 1970, 228 (5273) :764-&

[4]

GRAY RW, 1972, J BIOL CHEM, V247, P7528

[5] BIOLOGICAL-ACTIVITY OF LALPHA-HYDROXYCHOLECALCIFEROL, A SYNTHETIC ANALOG OF HORMONAL FORM OF VITAMIN-D [J].

HAUSSLER, MR ;

ZERWEKH, JE ;

HESSE, RH ;

RIZZARDO, E ;

PECHET, MM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (08) :2248-2252

[6]

Holick M F, 1974, Adv Steroid Biochem Pharmacol, V4, P111

[7]

HOLICK MF, 1973, J BIOL CHEM, V248, P6691

[8] VITAMIN-D METABOLISM [J].

HOLICK, MF ;

DELUCA, HF .

ANNUAL REVIEW OF MEDICINE, 1974, 25 :349-367

[9]

HOLICK MF, 1971, J LIPID RES, V12, P460

[10] 1 ALPHA-HYDROXY DERIVATIVE OF VITAMIN-D3 - HIGHLY POTENT ANALOG OF 1 ALPHA, 25-DIHYDROXYVITAMIN-D3 [J].

HOLICK, MF ;

SEMMLER, EJ ;

SCHNOES, HK ;

DELUCA, HF .

SCIENCE, 1973, 180 (4082) :190-191

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