IS THERE A CASE FOR A VIRUS ETIOLOGY IN MULTIPLE-SCLEROSIS

被引：7
作者：
SOUBERBIELLE, BE [1 ]
SZAWLOWSKI, PWS [1 ]
RUSSELL, WC [1 ]
机构：
[1] UNIV ST ANDREWS,SCH BIOL & MED SCI,DIV CELL & MOLEC BIOL,ST ANDREWS KY16 9AJ,FIFE,SCOTLAND
来源：
SCOTTISH MEDICAL JOURNAL | 1995年 / 40卷 / 02期
基金：
英国惠康基金;
关键词：
MULTIPLE SCLEROSIS; VIRUSES;
D O I：
10.1177/003693309504000207
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Multiple Sclerosis (MS) is a devastating demyelinating disease with a very high prevalence in North-East Scotland and in the Orkney and Shetland Islands. MS appears to be a multifactorial disorder with environmental and generic elements and it has been proposed that these, in tandem, provoke an autoimmune response giving rise to the disease. Although there is no direct evidence of a specific virus being involved in MS, there are nevertheless grounds for suspecting a viral association. This review discusses these aspects of MS and suggests that a more aggressive approach to unravelling the role of viruses is needed.
引用
收藏
页码：55 / 62
页数：8
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