N-[4-(3H-1,3,4-OXADIAZOLINE-2-THION-5-YL)PHENYL]-N'-SUBSTITUTED THIOUREAS - SYNTHESIS AND ANTIMICROBIOLOGICAL ACTIVITIES

被引：31

作者：

ROLLAS, S ^{[1
]}

BUYUKTIMKIN, S ^{[1
]}

CEVIKBAS, A ^{[1
]}

机构：

[1] UNIV ISTANBUL,FAC PHARM,ISTANBUL 34452,TURKEY

来源：

ARCHIV DER PHARMAZIE | 1991年 / 324卷 / 03期

关键词：

D O I：

10.1002/ardp.19913240312

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Diverse pharmacological properties are associated with 3H-1,3,4-oxadiazoline-2-thione derivatives. These include anticonvulsant1-4) and fungicidal5) properties. On the other hand thiourea derivatives possess antiphytoviral6), virucidal7), growth inhibitory8-10), and herbicide11) activities. All these data prompted us to combine these moieties into a single molecule. The compounds synthesized were tested for their antimicrobial activities against seven microorganisms.

引用

页码：189 / 190

页数：2

共 17 条

[1]

CHAUDHURY SK, 1978, J PHARM SCI, V67, P1505

[2]

CHRISTENSEN HE, 1974, TOXIC SUBSTANCES LIS, P477

[3]

DIGHE VS, 1963, CURR SCI INDIA, V32, P257

[4]

GARRIGUE G, 1984, PATHOL BIOL, V32, P643