REGIONAL DIFFERENCES IN THE DISTRIBUTION OF CAPSAICIN-SENSITIVE TARGET-IDENTIFIED ADULT-RAT DORSAL-ROOT GANGLION NEURONS

被引：24
|
作者：
HUTSAI, M [1 ]
WINTER, J [1 ]
WOOLF, CJ [1 ]
机构：
[1] SANDOZ INST MED MED RES,LONDON,ENGLAND
来源：
NEUROSCIENCE LETTERS | 1992年 / 143卷 / 1-2期
基金：
英国惠康基金;
关键词：
CAPSAICIN; DORSAL ROOT GANGLION; RETROGRADE LABELING; TARGET-IDENTIFIED; COBALT UPTAKE; CULTURE;
D O I：
10.1016/0304-3940(92)90276-D
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
A retrograde labelling technique combined with a cobalt uptake assay in cultured adult rat dorsal root ganglion (DRG) neurons were applied to study the distribution of capsaicin sensitivity in relation to different peripheral targets. This study shows that there are regional differences between skin, skeletal muscle and urinary bladder; 20-30% of skin afferents, 40% of muscle afferents and 60% of bladder afferents were found to be capsaicin-senditive. This may reflect differences in the proportion of chemosensitive afferents innervating different peripheral tissues.
引用
收藏
页码：251 / 254
页数：4
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