Structure and function of 5S rRNA in the ribosome

被引：47
作者：
Bogdanov, AA
Dontsova, OA
Dokudovskaya, SS
Lavrik, IN
机构：
[1] Department of Chemistry of Natural Compounds, School of Chemistry, Moscow State University
来源：
BIOCHEMISTRY AND CELL BIOLOGY | 1995年 / 73卷 / 11-12期
关键词：
58; rRNA; ribosomes; 23S rRNA; site-directed chemical cross-linking; RNA folding;
D O I：
10.1139/o95-094
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
5S rRNA is a small RNA molecule that is a component of a ribosome from almost all living organisms. In this review, we discuss the biogenesis of 5S rRNA and its properties as an independent structural domain of a ribosome as well as the current concepts concerning the higher order structure of 5S rRNA in free state and in its complexes with ribosomal proteins and its folding in the ribosome. Special attention is paid to recent experimental approaches that have been useful in 5S rRNA studies. Our own data on topography of 5S rRNA in the ribosomes are discussed in detail. The hypothesis describing the possible functional role of 5S rRNA for ribosome functioning is discussed.
引用
收藏
页码：869 / 876
页数：8
相关论文
共 60 条
[1]   ALTERATION OF 5S RNA CONFORMATION BY RIBOSOMAL-PROTEINS L18 AND L25 [J].
BEAR, DG ;
SCHLEICH, T ;
NOLLER, HF ;
GARRETT, RA .
NUCLEIC ACIDS RESEARCH, 1977, 4 (07) :2511-2526
[2]   CRYSTAL-STRUCTURE OF DOMAIN-A OF THERMUS-FLAVUS 5S RIBOSOMAL-RNA AND THE CONTRIBUTION OF WATER-MOLECULES TO ITS STRUCTURE [J].
BETZEL, C ;
LORENZ, S ;
FURSTE, JP ;
BALD, R ;
ZHANG, M ;
SCHNEIDER, TR ;
WILSON, KS ;
ERDMANN, VA .
FEBS LETTERS, 1994, 351 (02) :159-164
[3]   THE ROLE OF STABLE COMPLEXES THAT REPRESS AND ACTIVATE EUKARYOTIC GENES [J].
BROWN, DD .
CELL, 1984, 37 (02) :359-365
[4]  
BRUNEL C, 1991, J MOL BIOL, V221, P293
[5]   NEW METHOD FOR ISOLATION OF A 5 S RNA COMPLEX WITH PROTEINS L5, L18 AND L25 FROM ESCHERICHIA-COLI RIBOSOMES [J].
CHENSCHMEISSER, U ;
GARRETT, RA .
FEBS LETTERS, 1977, 74 (02) :287-291
[6]   DELINEATION OF STRUCTURAL DOMAINS IN EUKARYOTIC 5S RIBOSOMAL-RNA WITH A RHODIUM PROBE [J].
CHOW, CS ;
HARTMANN, KM ;
RAWLINGS, SL ;
HUBER, PW ;
BARTON, JK .
BIOCHEMISTRY, 1992, 31 (13) :3534-3542
[7]  
Christiansen J, 1986, STRUCTURE FUNCTION G, P253
[8]   STRUCTURAL-ANALYSIS OF 3 PROKARYOTIC 5S RIBOSOMAL-RNA SPECIES AND SELECTED 5S RIBOSOMAL-RNA RIBOSOMAL-PROTEIN COMPLEXES BY MEANS OF PB(II)-INDUCED HYDROLYSIS [J].
CIESIOLKA, J ;
LORENZ, S ;
ERDMANN, VA .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1992, 204 (02) :575-581
[9]   YEAST RIBOSOMAL-PROTEIN L1 IS REQUIRED FOR THE STABILITY OF NEWLY SYNTHESIZED 5S RIBOSOMAL-RNA AND THE ASSEMBLY OF 60S RIBOSOMAL-SUBUNITS [J].
DESHMUKH, M ;
TSAY, YF ;
PAULOVICH, AG ;
WOOLFORD, JL .
MOLECULAR AND CELLULAR BIOLOGY, 1993, 13 (05) :2835-2845
[10]   ROLE OF 5S RNA IN ASSEMBLY AND FUNCTION OF 50S SUBUNIT FROM ESCHERICHIA-COLI [J].
DOHME, F ;
NIERHAUS, KH .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (07) :2221-2225
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