NOVEL ANTIMYCIN ANTIBIOTICS, URAUCHIMYCIN-A AND URAUCHIMYCIN-B, PRODUCED BY MARINE ACTINOMYCETE

被引：64

作者：

IMAMURA, N

NISHIJIMA, M

ADACHI, K

SANO, H

机构：

[1] Shimizu Institute, Marine Biotechnology Institute Co., Ltd, Shimizu, 424, Meguro-ku

来源：

JOURNAL OF ANTIBIOTICS | 1993年 / 46卷 / 02期

关键词：

D O I：

10.7164/antibiotics.46.241

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Two novel antimycin antibiotics, urauchimycins A and B, were isolated from a fermentation broth of a Streptomyces sp. Ni-80. The strain was isolated from an unidentified sponge. Their chemical structures were determined by 2D NMR analysis. They are the first antimycin antibiotics which possess a branched side chain moiety. They exhibited inhibitory activity against morphological differentiation of Candida albicans.

引用

页码：241 / 246

页数：6

共 8 条

[1] H-1 AND C-13 RESONANCE DESIGNATION OF ANTIMYCIN-A1 BY TWO-DIMENSIONAL NMR-SPECTROSCOPY [J].