SYNTHESIS OF BETA-HYDROXY NITRILES VIA INDIUM-INDUCED COUPLING OF BROMOACETONITRILE WITH CARBONYL-COMPOUNDS

被引：22

作者：

ARAKI, S ^{[1
]}

YAMADA, M ^{[1
]}

BUTSUGAN, Y ^{[1
]}

机构：

[1] NAGOYA INST TECHNOL, DEPT APPL CHEM, GOKISO CHO, SHOWA KU, NAGOYA, AICHI 466, JAPAN

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 1994年 / 67卷 / 04期

关键词：

D O I：

10.1246/bcsj.67.1126

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The organoindium reagent, derived from indium metal and bromoacetoiiitrile, reacted with carbonyl compounds in the presence of chlorotrimethylsilane to give, after hydrolysis, beta-hydroxy nitriles. The coupling proceeded with high chemoselectivity, though the diastereoselectivity was low.

引用

页码：1126 / 1129

页数：4

共 25 条

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