MEASUREMENT OF RELAXATION-TIME CONSTANTS FOR METHYL-GROUPS BY PROTON-DETECTED HETERONUCLEAR NMR-SPECTROSCOPY

被引：56
|
作者：
PALMER, AG
WRIGHT, PE
RANCE, M
机构：
[1] Department of Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037
来源：
CHEMICAL PHYSICS LETTERS | 1991年 / 185卷 / 1-2期
基金：
美国国家科学基金会;
关键词：
D O I：
10.1016/0009-2614(91)80136-L
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
Experimental schemes are described that allow proton-detected NMR spectroscopy to measure accurately C-13 spin-lattice relaxation time constants of methyl groups. By using magic angle pulses in DEPT-based sequences, or analogously tuned delays in INEPT-based sequences, contributions to the observed NMR signal are eliminated that would otherwise complicate the measurement of the desired time constants. Experimental verification of the proposed techniques is provided by measurements on sodium acetate and on a peptide.
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页码：41 / 46
页数：6
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