Silver Nanoparticles and Mitochondrial Interaction

被引:77
作者
Bressan, Eriberto [1 ]
Ferroni, Letizia [2 ]
Gardin, Chiara [2 ]
Rigo, Chiara [3 ]
Stocchero, Michele [1 ]
Vindigni, Vincenzo [1 ]
Cairns, Warren [3 ]
Zavan, Barbara [2 ]
机构
[1] Univ Padua, Dept Biomed Sci, I-35100 Padua, Italy
[2] Univ Padua, Dept Neurosci, Via Venezia 90, I-35100 Padua, Italy
[3] Univ Ca Foscari, CNR IDPA, Dept Environm Sci Informat & Stat, I-30123 Venice, Italy
关键词
D O I
10.1155/2013/312747
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Nanotechnology has gone through a period of rapid growth, thus leading to the constant increase in the application of engineered nanomaterials in daily life. Several different types of nanoparticles have been engineered to be employed in a wide array of applications due to their high surface to volume ratio that leads to unique physical and chemical properties. So far, silver nanoparticles (AgNps) have been used in many more different medical devices than any other nanomaterial, mainly due to their antimicrobial properties. Despite the promising advantages posed by using AgNps in medical applications, the possible health effects associated with the inevitable human exposure to AgNps have raised concerns as to their use since a clear understanding of their specific interaction with biological systems has not been attained yet. In light of such consideration, aim of the present work is themorphological analysis of the intracellular behavior of AgNps with a diameter of 10 nm, with a special attention to their interaction with mitochondria.
引用
收藏
页数:8
相关论文
共 27 条
[1]   High glucose induces adipogenic differentiation of muscle-derived stem cells [J].
Aguiari, Paola ;
Leo, Sara ;
Zavan, Barbara ;
Vindigni, Vincenzo ;
Rimessi, Alessandro ;
Bianchi, Katiuscia ;
Franzin, Chiara ;
Cortivo, Roberta ;
Rossato, Marco ;
Vettor, Roberto ;
Abatangelo, Giovanni ;
Pozzan, Tullio ;
Pinton, Paolo ;
Rizzuto, Rosario .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (04) :1226-1231
[2]   The Use of Nanoparticles to Control Oral Biofilm Formation [J].
Allaker, R. P. .
JOURNAL OF DENTAL RESEARCH, 2010, 89 (11) :1175-1186
[3]   Effect of silver on burn wound infection control and healing: Review of the literature [J].
Atiyeh, Bishara S. ;
Costagliola, Michel ;
Hayek, Shady N. ;
Dibo, Saad A. .
BURNS, 2007, 33 (02) :139-148
[4]   Clinical outcomes of GBR procedures to correct peri-implant dehiscences and fenestrations: a systematic review [J].
Chiapasco, Matteo ;
Zaniboni, Marco .
CLINICAL ORAL IMPLANTS RESEARCH, 2009, 20 :113-123
[5]   Nanostructured Biomaterials for Tissue Engineered Bone Tissue Reconstruction [J].
Chiara, Gardin ;
Letizia, Ferroni ;
Lorenzo, Favero ;
Edoardo, Stellini ;
Diego, Stomaci ;
Stefano, Sivolella ;
Eriberto, Bressan ;
Barbara, Zavan .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2012, 13 (01) :737-757
[6]  
Cortivo R, 2010, NANOMEDICINE-UK, V5, P641, DOI [10.2217/nnm.10.32, 10.2217/NNM.10.32]
[7]  
Esposito M., 2010, COCHRANE DB SYST REV, V7
[8]   Uptake and intracellular distribution of silver nanoparticles in human mesenchymal stem cells [J].
Greulich, C. ;
Diendorf, J. ;
Simon, T. ;
Eggeler, G. ;
Epple, M. ;
Koeller, M. .
ACTA BIOMATERIALIA, 2011, 7 (01) :347-354
[9]   Silver Nanoparticles in Therapeutics: Development of an Antimicrobial Gel Formulation for Topical Use [J].
Jain, Jaya ;
Arora, Sumit ;
Rajwade, Jyutika M. ;
Omray, Pratibha ;
Khandelwal, Sanjeev ;
Paknikar, Kishore M. .
MOLECULAR PHARMACEUTICS, 2009, 6 (05) :1388-1401
[10]   Oxidative stress-dependent toxicity of silver nanoparticles in human hepatoma cells [J].
Kim, Soohee ;
Choi, Ji Eun ;
Choi, Jinhee ;
Chung, Kyu-Hyuck ;
Park, Kwangsik ;
Yi, Jongheop ;
Ryu, Doug-Young .
TOXICOLOGY IN VITRO, 2009, 23 (06) :1076-1084