ANTIBACTERIAL ACTIVITY OF CEFCANEL

被引:1
|
作者
BERGAN, T [1 ]
DAFONSECA, J [1 ]
机构
[1] UNIV OSLO,INST PHARM,DEPT MICROBIOL,OSLO 3,NORWAY
关键词
CEPHALOSPORINS; ENTEROBACTERIACEAE; STREPTOCOCCUS; ANTIBIOTICS; SUSCEPTIBILITY; PSEUDOMONAS; HAEMOPHILUS; CEFCANEL;
D O I
10.1159/000239109
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The minimum inhibitory concentration of cefcanel, a new oral cephalosporin, has been determined for 182 clinical isolates, of which 84 were from the family Enterobacteriaceae, 45 were from the genus Streptococcus, 18 were nonfermentative rods, 25 were Haemophilus influenzae and 10 were Branhamella catarrhalis. In general, cefcanel was more active than the other cephalosporins against the species Escherichia coli, Klebsiella aerogenes and Proteus mirabilis. Among the genus Streptococcus only the enterococci were resistant to cefcanel. H. influenzae and B. catarrhalis showed also a reasonable susceptibility towards cefcanel. Oxidative rods were highly resistant to cefcanel.
引用
收藏
页码:96 / 104
页数:9
相关论文
共 50 条
  • [1] EFFICACY OF CEFCANEL ON STAPHYLOCOCCI
    BERGAN, T
    DAFONSECA, J
    CHEMOTHERAPY, 1991, 37 (01) : 43 - 49
  • [2] ANTIBACTERIAL ACTIVITY OF CEFEPIME IN-VITRO
    LIU, YC
    HUANG, WK
    CHENG, DL
    CHEMOTHERAPY, 1994, 40 (06) : 384 - 390
  • [3] Synthesis and antibacterial activity of catecholate-ciprofloxacin conjugates
    Fardeau, Sylvain
    Dassonville-Klimpt, Alexandra
    Audic, Nicolas
    Sasaki, Andre
    Pillon, Marine
    Baudrin, Emmanuel
    Mullie, Catherine
    Sonnet, Pascal
    BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 22 (15) : 4049 - 4060
  • [4] Optimization of LpxC Inhibitors for Antibacterial Activity and Cardiovascular Safety
    Cohen, Frederick
    Aggen, James B.
    Andrews, Logan D.
    Assar, Zahra
    Boggs, Jen
    Choi, Taylor
    Dozzo, Paola
    Easterday, Ashton N.
    Haglund, Cat M.
    Hildebrandt, Darin J.
    Holt, Melissa C.
    Joly, Kristin
    Jubb, Adrian
    Kamal, Zeeshan
    Kane, Timothy R.
    Konradi, Andrei W.
    Krause, Kevin M.
    Linsell, Martin S.
    Machajewski, Timothy D.
    Miroshnikova, Olga
    Moser, Heinz E.
    Nieto, Vincent
    Thu Phan
    Plato, Craig
    Serio, Alisa W.
    Seroogy, Julie
    Shakhmin, Anton
    Stein, Adam J.
    Sun, Alex D.
    Sviridov, Serguei
    Wang, Zhan
    Wlasichuk, Kenneth
    Yang, Wen
    Zhou, Xiaoming
    Zhu, Hai
    Cirz, Ryan T.
    CHEMMEDCHEM, 2019, 14 (16) : 1560 - 1572
  • [5] Labradorins with Antibacterial Activity Produced by Pseudomonas sp.
    Broberg, Anders
    Bjerketorp, Joakim
    Andersson, Pierre
    Sahlberg, Christer
    Levenfors, Jolanta J.
    MOLECULES, 2017, 22 (07):
  • [6] Development of antibacterial peptides with efficient antibacterial activity, low toxicity, high membrane disruptive activity and a synergistic antibacterial effect
    Wang, Hao
    Niu, Mingcong
    Xue, Tong
    Ma, Linhao
    Gu, Xiulian
    Wei, Guangcheng
    Li, Fengqiao
    Wang, Chunhua
    JOURNAL OF MATERIALS CHEMISTRY B, 2022, 10 (11) : 1858 - 1874
  • [7] Synthesis and antibacterial activity of 1,8-naphthyridine cephalosporins
    Park, JK
    Im, SK
    Ju, H
    Jeon, JM
    Kim, CG
    Kim, DU
    Yoo, JC
    Cho, SS
    Cho, SK
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 2005, 26 (03): : 371 - 372
  • [8] Investigation of the antibacterial activity of pioglitazone
    Masadeh, Majed M.
    Mhaidat, Nizar M.
    Al-Azzam, Sayer I.
    Alzoubi, Karem H.
    DRUG DESIGN DEVELOPMENT AND THERAPY, 2011, 5 : 421 - 425
  • [9] Optical control of antibacterial activity
    Velema, Willem A.
    van der Berg, Jan Pieter
    Hansen, Mickel J.
    Szymanski, Wiktor
    Driessen, Arnold J. M.
    Feringa, Ben L.
    NATURE CHEMISTRY, 2013, 5 (11) : 924 - 928
  • [10] In vitro and in vivo antibacterial activity of modithromycin against streptococci and Haemophilus influenzae
    Sato, Takafumi
    Kawai, Yui
    Matsuda, Hayato
    Tateda, Kazuhiro
    Kimura, Soichiro
    Ishii, Yoshikazu
    Yamaguchi, Keizo
    Gotoh, Naomasa
    JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2011, 66 (07) : 1547 - 1554