CYTOKINES AND IG SWITCHING - EVOLUTIONARY DIVERGENCE BETWEEN MICE AND HUMANS

被引：46
作者：
CALLARD, RE
TURNER, MW
机构：
[1] Department of Immunology, Institute of Child Health, London, WC1N 1EH
来源：
IMMUNOLOGY TODAY | 1990年 / 11卷 / 06期
关键词：
D O I：
10.1016/0167-5699(90)90082-K
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Cytokines exert control over many aspects of immunoglobulin regulation, including isotype switching. But is the same mechanism used in subclass regulation in mice and humans? Robin Callard and Malcolm Turner think not, and here caution against the wholesale application of murine studies to humans. © 1990.
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页码：200 / 203
页数：4
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