LIMITED ROLE OF FETAL BLOOD-SAMPLING IN PREDICTION OF OUTCOME IN INTRAUTERINE GROWTH-RETARDATION

被引：71

作者：

NICOLINI, U ^{[1
]}

NICOLAIDIS, P ^{[1
]}

FISK, NM ^{[1
]}

VAUGHAN, JI ^{[1
]}

FUSI, L ^{[1
]}

GLEESON, R ^{[1
]}

RODECK, CH ^{[1
]}

机构：

[1] HAMMERSMITH HOSP,LONDON W12 0HS,ENGLAND

来源：

LANCET | 1990年 / 336卷 / 8718期

关键词：

D O I：

10.1016/0140-6736(90)93239-L

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Fetal acid-base status was evaluated on 66 blood samples taken for rapid karyotyping from 58 growth-retarded fetuses. Before blood sampling, doppler blood flow studies of the umbilical artery showed end-diastolic frequencies to be absent in 32 fetuses (group 1) and present in 26 (group 2). Fetuses with chromosomal (n=4) or structural (n=8) abnormalities were excluded from subsequent analysis. Gestational age at blood sampling (27·8 [95% Cl 26·5-29·1] vs 32·2 [30·4-34·1] weeks) and time from sampling to delivery (median 2 (range 0-35] vs 14 [0-77] days) were significantly lower in group 1 than group 2. There were no perinatal deaths in group 2 whereas mortality in group 1 was 65·4%. There were significant differences between the groups at blood sampling in pH, pO2, pCO2, base equivalents, and nucleated-red-cell count, but within group 1 these measurements were similar in surviving fetuses and those who died perinatally. Since acid-base determination does not predict perinatal outcome in growth-retarded fetuses, fetal blood sampling has a limited role in monitoring fetal wellbeing. © 1990.

引用

页码：768 / 772

页数：5

共 26 条

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