One-year Outcome of Stenting for Long Coronary Lesions, a Prospective Clinical Trial

被引:0
作者
Ghaffari, Samad [1 ]
Hasanian, Mohammad Reza [1 ]
Pourafkari, Leili [1 ]
机构
[1] Tabriz Univ Med Sci Tabriz, Cardiovasc Res Ctr, Tabriz, Iran
关键词
Coronary Artery Disease; Restenosis; Long Lesion;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Percutaneous coronary intervention (PCI) for long coronary lesions is associated with poor angiographic and clinical outcome compared with focal lesions. Here we describe our experience in PCI of such lesions with bare (BMS) or drug eluting stents (DES). Methods: Between October 2008 and September 2009, One hundred patients with one significant coronary artery stenosis of longer than 20 mm were enrolled in this prospective study. Demographic, clinical and angiographic data were collected and the rate of ischemic events and major adverse cardiac events (MACE) were evaluated in a mean follow up period of about 11.3 +/- 3.2 months. Results: Mean age of participants was 58.08 +/- 8.97 years. Seventy two (72%) patients were male and the remainders were females. Majority of patients underwent DES implantation [25 (25%) BMS, 75 (75%) DES, P<0.001)]. There was no difference in frequency of major risk factors distribution among DES or BMS groups. Mean diameter of implanted stent was 2.8 +/- 0.033mm in DES group and 2.9 +/- 0.35 in group with BMS (P=0.214). The mean length of implanted stent was 25.8 +/- 3.08mm in DES and 23.36 +/- 0. mm in BMS groups (P<0.001). In-stent restenosis rate was significantly higher in BMS group [6(24%) in BMS and 5(6.9%) in DES, P=0.02]. MACE were observed in 7(9.3%) of patients with DES and 7 (28%) of patients with BMS (P=0.04). Conclusion: In long coronary lesions implantation of DES was associated with lower MACE compared with BMS in one year follow up. Studies with longer term follow up are needed to further clarify this issue.
引用
收藏
页码:7 / 12
页数:6
相关论文
共 31 条
[1]   ACUTE ANGIOGRAPHIC AND CLINICAL-RESULTS OF LONG BALLOON PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY AND ADJUVANT STENTING FOR LONG NARROWINGS [J].
CANNON, AD ;
ROUBIN, GS ;
HEARN, JA ;
IYER, SS ;
BAXLEY, WA ;
DEAN, LS .
AMERICAN JOURNAL OF CARDIOLOGY, 1994, 73 (09) :635-641
[2]   Clinical efficacy of polymer-based paclitaxel-eluting stents in the treatment of complex, long coronary artery lesions from a multicenter, randomized trial - Support for the use of drug-eluting Stents in contemporary clinical practice [J].
Dawkins, KD ;
Grube, E ;
Guagliumi, G ;
Banning, AP ;
Zmudka, K ;
Colombo, A ;
Thuesen, L ;
Hauptman, K ;
Marco, J ;
Wijns, W ;
Popma, JJ ;
Koglin, J ;
Russell, ME .
CIRCULATION, 2005, 112 (21) :3306-3313
[3]   INCIDENCE AND CONSEQUENCES OF PERIPROCEDURAL OCCLUSION - THE 1985-1986 NATIONAL HEART, LUNG, AND BLOOD INSTITUTE PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY REGISTRY [J].
DETRE, KM ;
HOLMES, DR ;
HOLUBKOV, R ;
COWLEY, MJ ;
BOURASSA, MG ;
FAXON, DP ;
DORROS, GR ;
BENTIVOGLIO, LG ;
KENT, KM ;
MYLER, RK .
CIRCULATION, 1990, 82 (03) :739-750
[4]   Paclitaxel-eluting or sirolimus-eluting stents to prevent restenosis in diabetic patients [J].
Dibra, A ;
Kastrati, A ;
Mehilli, J ;
Pache, J ;
Schühlen, H ;
von Beckerath, N ;
Ulm, K ;
Wessely, R ;
Dirschinger, J ;
Schömig, A .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 353 (07) :663-670
[5]  
Eeckhout E, 1996, CATHETER CARDIO DIAG, V39, P302
[6]   ANGIOGRAPHIC AND CLINICAL PREDICTORS OF ACUTE CLOSURE AFTER NATIVE VESSEL CORONARY ANGIOPLASTY [J].
ELLIS, SG ;
ROUBIN, GS ;
KING, SB ;
DOUGLAS, JS ;
WEINTRAUB, WS ;
THOMAS, RG ;
COX, WR .
CIRCULATION, 1988, 77 (02) :372-379
[7]   RESTENOSIS AFTER PLACEMENT OF PALMAZ-SCHATZ STENTS IN NATIVE CORONARY-ARTERIES - INITIAL RESULTS OF A MULTICENTER EXPERIENCE [J].
ELLIS, SG ;
SAVAGE, M ;
FISCHMAN, D ;
BAIM, DS ;
LEON, M ;
GOLDBERG, S ;
HIRSHFELD, JW ;
CLEMAN, MW ;
TEIRSTEIN, PS ;
WALKER, C ;
BAILEY, S ;
BUCHBINDER, M ;
TOPOL, EJ ;
SCHATZ, RA .
CIRCULATION, 1992, 86 (06) :1836-1844
[8]   A RANDOMIZED COMPARISON OF CORONARY-STENT PLACEMENT AND BALLOON ANGIOPLASTY IN THE TREATMENT OF CORONARY-ARTERY DISEASE [J].
FISCHMAN, DL ;
LEON, MB ;
BAIM, DS ;
SCHATZ, RA ;
SAVAGE, MP ;
PENN, I ;
DETRE, K ;
VELTRI, L ;
RICCI, D ;
NOBUYOSHI, M ;
CLEMAN, M ;
HEUSER, R ;
ALMOND, D ;
TEIRSTEIN, PS ;
FISH, RD ;
COLOMBO, A ;
BRINKER, J ;
MOSES, J ;
SHAKNOVICH, A ;
HIRSHFELD, J ;
BAILEY, S ;
ELLIS, S ;
RAKE, R ;
GOLDBERG, S .
NEW ENGLAND JOURNAL OF MEDICINE, 1994, 331 (08) :496-501
[9]   The influence of stent length on clinical and angiographic outcome in patients undergoing elective stenting for native coronary artery lesions - Final results of the Magic 5L Study [J].
Foley, DP ;
Pieper, M ;
Wijns, W ;
Suryapranata, H ;
Grollier, G ;
Legrand, V ;
de Scheerder, I ;
Hanet, C ;
Puel, J ;
Mudra, H ;
Bonnier, HJRM ;
Colombo, A ;
Thomas, M ;
Probst, P ;
Morice, MC ;
Kleijne, J ;
Serruys, PW .
EUROPEAN HEART JOURNAL, 2001, 22 (17) :1585-1593
[10]   A prospective randomized comparison between paclitaxel and sirolimus stents in the real world of interventional cardiology -: The TAXi trial [J].
Goy, JJ ;
Stauffier, JC ;
Siegenthaler, M ;
Benoît, A ;
Seydoux, C .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 45 (02) :308-311