EFFECTS OF POPULATION-STRUCTURE ON DNA FINGERPRINT ANALYSIS IN FORENSIC-SCIENCE

被引：46

作者：

NICHOLS, RA ^{[1
]}

BALDING, DJ ^{[1
]}

机构：

[1] UNIV LONDON,QUEEN MARY & WESTFIELD COLL,SCH MATH SCI,LONDON E1 4NS,ENGLAND

来源：

HEREDITY | 1991年 / 66卷

关键词：

DNA PROFILES; FORENSIC SCIENCE; MINISATELLITES; POPULATION GENETICS;

D O I：

10.1038/hdy.1991.37

中图分类号：

Q14 [生态学（生物生态学）];

学科分类号：

071012 ; 0713 ;

摘要：

DNA fingerprints are used in forensic science to identify individuals. However, current analyses could underestimate the probability of two individuals sharing the same profile because the effect of population structure is not incorporated. An alternative analysis is proposed to take into account population stratification. The analysis uses studies of inbreeding in human populations to obtain an empirical upper bound on the magnitude of the effect.

引用

页码：297 / 302

页数：6

共 18 条

[1]

BALAZS I, 1989, AM J HUM GENET, V44, P182

[2]

Cavalli-Sforza L.L., 1971, GENETICS HUMAN POPUL

[3]

COHEN JE, 1990, AM J HUM GENET, V46, P358

[4] NO EXCESS OF HOMOZYGOSITY AT LOCI USED FOR DNA FINGERPRINTING [J].

DEVLIN, B ;

RISCH, N ;

ROEDER, K .

SCIENCE, 1990, 249 (4975) :1416-1420

[5] DNA FINGERPRINTING ON TRIAL [J].

EVETT, IW ;

WERRETT, DJ ;

GILL, P ;

BUCKLETON, JS .

NATURE, 1989, 340 (6233) :435-435

[6]

GILL P, 1990, HUM GENET, V85, P75

[7] REPEAT UNIT SEQUENCE VARIATION IN MINISATELLITES - A NOVEL SOURCE OF DNA POLYMORPHISM FOR STUDYING VARIATION AND MUTATION BY SINGLE MOLECULE ANALYSIS [J].

JEFFREYS, AJ ;

NEUMANN, R ;

WILSON, V .

CELL, 1990, 60 (03) :473-485

[8] INDIVIDUAL-SPECIFIC FINGERPRINTS OF HUMAN DNA [J].

JEFFREYS, AJ ;

WILSON, V ;

THEIN, SL .

NATURE, 1985, 316 (6023) :76-79

[9] HYPERVARIABLE MINISATELLITE REGIONS IN HUMAN DNA [J].

JEFFREYS, AJ ;

WILSON, V ;

THEIN, SL .

NATURE, 1985, 314 (6006) :67-73

[10] INBREEDING IN THE UTAH MORMONS - AN EVALUATION OF ESTIMATES BASED ON PEDIGREES, ISONYMY, AND MIGRATION MATRICES [J].

JORDE, LB .

ANNALS OF HUMAN GENETICS, 1989, 53 :339-355

← 1 2 →