EFFECTS OF MR EXPOSURE ON AXONAL OUTGROWTH IN THE SYMPATHETIC NERVOUS-SYSTEM OF THE CHICK

被引：16

作者：

YIP, YP ^{[1
]}

CAPRIOTTI, C ^{[1
]}

YIP, JW ^{[1
]}

机构：

[1] UNIV PITTSBURGH, SCH MED, DEPT NEUROBIOL, PITTSBURGH, PA 15261 USA

来源：

JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING | 1995年 / 5卷 / 04期

关键词：

BIOLOGICAL EFFECTS; NERVOUS SYSTEM;

D O I：

10.1002/jmri.1880050416

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The effects of MR exposure on the rate and specificity of sympathetic preganglionic axonal outgrowth were examined in the chick embryo. Embryos were exposed to a static magnetic field of 1.5 T for 6 hours, 64 MHz RF field pulses, and a switched magnetic field gradient of amplitude 0.6 G/cm for 4 hours. No significant difference in axonal outgrowth was observed between MR-exposed and control embryos. In addition, the distributions of several major extracellular matrix (ECM) molecules, laminin, fibronectin, and collagen IV, were examined. Immunostaining patterns of these ECM molecules during axonal outgrowth showed no difference between MR-exposed and control embryos. Our results suggest that the MR exposure conditions used in this study do not affect axonal outgrowth in the sympathetic nervous system of the chick.

引用

页码：457 / 462

页数：6

共 37 条

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