PROTEOLYSIS - THE PROTEASOME - A PROTEIN-DEGRADING ORGANELLE

被引：135
作者：
RUBIN, DM
FINLEY, D
机构：
[1] Department of Cell Biology, Harvard Medical School, Boston, MA 02115
来源：
CURRENT BIOLOGY | 1995年 / 5卷 / 08期
关键词：
D O I：
10.1016/S0960-9822(95)00172-2
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The crystal structure of the proteasome suggests that degradation of ubiquitin-protein conjugates is achieved by unfolding the protein substrate and translocating it through a channel into a peptidase-containing chamber.
引用
收藏
页码：854 / 858
页数：5
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