THE PHASE-BEHAVIOR OF L-ALPHA-PHOSPHATIDYLCHOLINE IN THE PRESENCE OF CHLORPROMAZINE UNDER DIFFERENT EXPERIMENTAL CONDITIONS

被引：1

作者：

ADHIKARY, G ^{[1
]}

CHANDRA, S ^{[1
]}

SIKDAR, R ^{[1
]}

SEN, PC ^{[1
]}

机构：

[1] BOSE INST,DEPT CHEM,CALCUTTA 700009,W BENGAL,INDIA

来源：

COLLOIDS AND SURFACES B-BIOINTERFACES | 1995年 / 4卷 / 06期

关键词：

CHLORPROMAZINE; LIPOSOMES; PHASE TRANSITION; PHOSPHATIDYLCHOLINE;

D O I：

10.1016/0927-7765(95)01191-K

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The phase behaviour of L-alpha-phosphatidylcholine liposomes has been studied as a function of temperature, pH, ionic strength, etc., in the presence and absence of chlorpromazine by a polarization method using 1,6-diphenyl-1,3,5-hexatriene as a fluorescence probe. The gel crystalline to liquid crystalline (T-c), liquid crystalline to cubic (T-II), and cubic to hexagonal (H-II) transition temperatures in multilayer liposomes have been detected, and are found to be affected by chlorpromazine under different experimental conditions.

引用

页码：335 / 339

页数：5

共 21 条

[1]

ADHIKARY G, 1991, BIOCHEM INT, V25, P951

[2] MEMBRANE CONTACT, FUSION, AND HEXAGONAL (HII) TRANSITIONS IN PHOSPHATIDYLETHANOLAMINE LIPOSOMES [J].