SITE-SELECTIVE HYDROLYSIS OF TRANSFER-RNA BY LANTHANIDE METAL-COMPLEXES

被引：52

作者：

HAYASHI, N

TAKEDA, N

SHIIBA, T

YASHIRO, M

WATANABE, K

KOMIYAMA, M

机构：

[1] UNIV TOKYO, FAC ENGN, DEPT IND CHEM, TOKYO 113, JAPAN

[2] TOKYO INST TECHNOL, DEPT LIFE CHEM, YOKOHAMA, KANAGAWA 227, JAPAN

[3] UNIV TSUKUBA, INST MAT SCI, TSUKUBA, IBARAKI 305, JAPAN

来源：

INORGANIC CHEMISTRY | 1993年 / 32卷 / 26期

关键词：

D O I：

10.1021/ic00078a002

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

tRNA(Phe) is site-selectively hydrolyzed by lanthanide metal complexes (Ce(III), Eu(III), La(III)) of hexamine macrocyclic ligands. The selectivities of the complexes are much higher than those of the metal ions and are strongly dependent on the ligand structure. The tertiary structure of tRNA is essential for the site-selective scission.

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页码：5899 / 5900

页数：2

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