EFFECTS OF DIAZEPAM AND D-AMPHETAMINE ON RHYTHMIC PATTERN OF EYE-MOVEMENTS IN GOLDFISH

被引：17

作者：

SALAS, C

NAVARRO, F

TORRES, B

DELGADOGARCIA, JM

机构：

[1] Laboratory of Neuroscience, Department of Animal Physiology and Biology, University of Seville, Seville, 41012

来源：

NEUROREPORT | 1992年 / 3卷 / 02期

关键词：

EYE MOVEMENT; OCULOMOTOR SYSTEM; CENTRAL PATTERN GENERATOR; FISH; D-AMPHETAMINE SULFATE; DIAZEPAM; FOURIER ANALYSIS;

D O I：

10.1097/00001756-199202000-00002

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

THE effects of diazepam and D-amphetamine on spontaneous, vestibular- and visually-induced eye movements were studied in the restrained goldfish. These animals showed a stereotyped pattern of spontaneous eye movements that scanned the visual field in the horizontal plane. Fourier analysis of these eve movements revealed a rhythmic pattern of about 5 cycles per minute, whose frequency increased to double and decreased to half following treatment with diazepam and D-amphetamine, respectively. However, the fast and slow components of vestibulo-ocular and optokinetic reflexes, as well as peculiar blink-like movements, remained unchanged at the same drug doses. These results suggest the presence of a central pattern generator for spontaneous eye movements in the goldfish, whose oscillation frequency is pharmacologically modifiable.

引用

页码：131 / 134

页数：4

共 22 条

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