Methemoglobinemia in a Pediatric Oncology Patient Receiving Sulfamethoxazole/Trimethoprim Prophylaxis

被引：5

作者：

Carroll, Timothy G. ^{[1
]}

Carroll, Megan G. ^{[1
]}

机构：

[1] Univ Oklahoma, Hlth Sci Ctr, Dept Pediat, Sect Crit Care, Oklahoma City, OK USA

来源：

AMERICAN JOURNAL OF CASE REPORTS | 2016年 / 17卷

关键词：

Antibiotic Prophylaxis; Methemoglobin; Methemoglobinemia; Pediatrics; Trimethoprim-Sulfamethoxazole Combination;

D O I：

10.12659/AJCR.897820

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Objective: Unusual or unexpected effect of treatment Background: Methemoglobinemia due to the administration of sulfamethoxazole/trimethoprim has been documented in a series of case reports. However, all of these reports are on adult patients, and all patients received at least daily administration of sulfamethoxazole/trimethoprim for the treatment of active or suspected infection. Case Report: Herein we report the development of methemoglobinemia in a pediatric patient receiving sulfamethoxazole/trimethoprim three times weekly for the prophylaxis of opportunistic infections. Conclusions: The clinician should always consider sulfamethoxazole/trimethoprim, even when administered for opportunistic infection prophylaxis at reduced doses and intervals, as a possible cause of methemoglobinemia.

引用

页码：499 / 502

页数：4

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