EFFECT OF IMMUNOGLOBULIN ADMINISTRATION ON BLOOD RHEOLOGY IN PATIENTS WITH SEPTIC SHOCK

被引：0

作者：

MADL, C ^{[1
]}

KOPPENSTEINER, R ^{[1
]}

WENDELIN, B ^{[1
]}

LENZ, K ^{[1
]}

KRAMER, L ^{[1
]}

GRIMM, G ^{[1
]}

KRANZ, A ^{[1
]}

SCHNEEWEISS, B ^{[1
]}

EHRINGER, H ^{[1
]}

机构：

[1] UNIV VIENNA, DEPT ANGIOL, A-1090 VIENNA, AUSTRIA

来源：

CIRCULATORY SHOCK | 1993年 / 40卷 / 04期

关键词：

FIBRINOGEN; PLASMA VISCOSITY; RED CELL AGGREGATION;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The hemorrheological determinants plasma fibrinogen, plasma viscosity, red cell aggregation, and hematocrit were studied in 11 patients before and 4 and 24 hr after a 15 g immunoglobulin infusion to assess the effect of intravenous immunoglobulin administration on blood rheology in septic shock. Four hr after the immunoglobulin administration, plasma fibrinogen decreased significantly [472 (175-950) vs. 522 (182-1,050) mg/dl before administration; median (range); P < 0.01]; after 24 hr, plasma fibrinogen tended to increase again [501 (185-980); n.s.]. No changes were seen in plasma viscosity, red cell aggregation, hematocrit, and coagulation status 4 and 24 hr after immunoglobulin administration. In patients with septic shock, intravenous immunoglobulin administration leads to a decrease in plasma fibrinogen, whereas plasma viscosity and red cell aggregation remain unaffected. The explanation for the decrease in fibrinogen remains speculative. (C) 1993 Wiley-Liss, Inc.

引用

页码：264 / 267

页数：4