EFFECT OF IMMUNOGLOBULIN ADMINISTRATION ON BLOOD RHEOLOGY IN PATIENTS WITH SEPTIC SHOCK

被引:0
作者
MADL, C [1 ]
KOPPENSTEINER, R [1 ]
WENDELIN, B [1 ]
LENZ, K [1 ]
KRAMER, L [1 ]
GRIMM, G [1 ]
KRANZ, A [1 ]
SCHNEEWEISS, B [1 ]
EHRINGER, H [1 ]
机构
[1] UNIV VIENNA, DEPT ANGIOL, A-1090 VIENNA, AUSTRIA
关键词
FIBRINOGEN; PLASMA VISCOSITY; RED CELL AGGREGATION;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The hemorrheological determinants plasma fibrinogen, plasma viscosity, red cell aggregation, and hematocrit were studied in 11 patients before and 4 and 24 hr after a 15 g immunoglobulin infusion to assess the effect of intravenous immunoglobulin administration on blood rheology in septic shock. Four hr after the immunoglobulin administration, plasma fibrinogen decreased significantly [472 (175-950) vs. 522 (182-1,050) mg/dl before administration; median (range); P < 0.01]; after 24 hr, plasma fibrinogen tended to increase again [501 (185-980); n.s.]. No changes were seen in plasma viscosity, red cell aggregation, hematocrit, and coagulation status 4 and 24 hr after immunoglobulin administration. In patients with septic shock, intravenous immunoglobulin administration leads to a decrease in plasma fibrinogen, whereas plasma viscosity and red cell aggregation remain unaffected. The explanation for the decrease in fibrinogen remains speculative. (C) 1993 Wiley-Liss, Inc.
引用
收藏
页码:264 / 267
页数:4
相关论文
共 35 条
  • [21] EFFECT OF INTRAVENOUS IMMUNOGLOBULIN ON INHIBITION OF FIBRINOGEN BINDING TO PLATELETS BY SERA FROM PATIENTS WITH IMMUNE THROMBOCYTOPENIA
    KAMIYAMA, M
    YOSHIMURA, Y
    CHEN, K
    ARKEL, YS
    AMERICAN JOURNAL OF HEMATOLOGY, 1993, 44 (02) : 77 - 84
  • [22] Prognostic value of APTT combined with fibrinogen and creatinine in predicting 28-Day mortality in patients with septic shock caused by acute enteric perforation
    Shuiqiao Fu
    Wenqiao Yu
    Qinghui Fu
    Zhipeng Xu
    Shaoyang Zhang
    Ting-bo Liang
    BMC Surgery, 23
  • [23] Prognostic value of APTT combined with fibrinogen and creatinine in predicting 28-Day mortality in patients with septic shock caused by acute enteric perforation
    Fu, Shuiqiao
    Yu, Wenqiao
    Fu, Qinghui
    Xu, Zhipeng
    Zhang, Shaoyang
    Liang, Ting-bo
    BMC SURGERY, 2023, 23 (01)
  • [24] Coagulation profiles in patients with sepsis/septic shock identify mixed hypo-hypercoagulation patterns based on rotational thromboelastometry: A prospective observational study
    Bui-Thi, Hanh-Duyen
    Gia, Kien To
    Minh, Khoi Le
    THROMBOSIS RESEARCH, 2023, 227 : 51 - 59
  • [25] The effect of sulfur baths on hemorheological properties of blood in patients with osteoarthritis
    Teleglow, Aneta
    Seremak, Joanna
    Golec, Joanna
    Marchewka, Jakub
    Golec, Piotr
    Marchewka, Urszula
    Maciejczyk, Marcin
    Golec, Edward
    SCIENTIFIC REPORTS, 2023, 13 (01)
  • [26] The effect of diuretics on red blood cell microrheological parameters in female hypertensive patients
    Muravyov, AV
    Yakusevich, VV
    Kabanov, AV
    Petrochenko, AS
    CLINICAL HEMORHEOLOGY AND MICROCIRCULATION, 2005, 33 (02) : 121 - 126
  • [27] Prospective Evaluation of Blood Coagulability and Effect of Treatment in Patients with Stroke Using Rotational Thromboelastometry
    Stanford, Sophia N.
    Sabra, Ahmed
    Lawrence, Matthew
    Morris, Roger H. K.
    Storton, Sharon
    Wani, Mushtaq
    Hawkins, Karl
    Williams, Phylip Rhodri
    Potter, John F.
    Evans, Phillip A.
    JOURNAL OF STROKE & CEREBROVASCULAR DISEASES, 2015, 24 (02) : 304 - 311
  • [28] Effect of emergency department fibrinogen testing on survival of trauma patients receiving blood transfusions
    White, Nathan J.
    Chien, Diana
    Hess, John R.
    BLOOD COAGULATION & FIBRINOLYSIS, 2020, 31 (06) : 372 - 376
  • [29] Effects of fibrinogen supplementation on clot formation in blood samples from cardiac surgery patients before and after tranexamic acid administration
    Walden, K.
    Hakimi, C. Shams
    Jeppsson, A.
    Karlsson, M.
    TRANSFUSION MEDICINE, 2019, 29 (05) : 319 - 324
  • [30] Effect of barnidipine on blood pressure and serum metabolic parameters in patients with essential hypertension: A pilot study
    Spirou, Athanasia
    Rizos, Evangelos
    Liberopoulos, Evangelos N.
    Kolaitis, Nikolaos
    Achimastos, Apostolos
    Tselepis, Alexandros D.
    Elisaf, Moses
    JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS, 2006, 11 (04) : 256 - 261