共 35 条
EFFECT OF IMMUNOGLOBULIN ADMINISTRATION ON BLOOD RHEOLOGY IN PATIENTS WITH SEPTIC SHOCK
被引:0
作者:
MADL, C
[1
]
KOPPENSTEINER, R
[1
]
WENDELIN, B
[1
]
LENZ, K
[1
]
KRAMER, L
[1
]
GRIMM, G
[1
]
KRANZ, A
[1
]
SCHNEEWEISS, B
[1
]
EHRINGER, H
[1
]
机构:
[1] UNIV VIENNA, DEPT ANGIOL, A-1090 VIENNA, AUSTRIA
关键词:
FIBRINOGEN;
PLASMA VISCOSITY;
RED CELL AGGREGATION;
D O I:
暂无
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
The hemorrheological determinants plasma fibrinogen, plasma viscosity, red cell aggregation, and hematocrit were studied in 11 patients before and 4 and 24 hr after a 15 g immunoglobulin infusion to assess the effect of intravenous immunoglobulin administration on blood rheology in septic shock. Four hr after the immunoglobulin administration, plasma fibrinogen decreased significantly [472 (175-950) vs. 522 (182-1,050) mg/dl before administration; median (range); P < 0.01]; after 24 hr, plasma fibrinogen tended to increase again [501 (185-980); n.s.]. No changes were seen in plasma viscosity, red cell aggregation, hematocrit, and coagulation status 4 and 24 hr after immunoglobulin administration. In patients with septic shock, intravenous immunoglobulin administration leads to a decrease in plasma fibrinogen, whereas plasma viscosity and red cell aggregation remain unaffected. The explanation for the decrease in fibrinogen remains speculative. (C) 1993 Wiley-Liss, Inc.
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页码:264 / 267
页数:4
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