INVESTIGATION OF THE REGIOSELECTIVITY OF SOME ESTERIFICATIONS INVOLVING METHYL 4,6-O-BENZYLIDENE D-PYRANOSIDES AND PSEUDOMONAS-FLUORESCENS LIPASE

被引：13

作者：

IACAZIO, G

ROBERTS, SM

机构：

[1] Department of Chemistry, University of Exeter, Exeter, Devon EX4 4QD, Stocker Road

[2] ENSSPICAM, 13397, Marseille, Cedex 13, Av. Escadrille Normandie-Niemen

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1993年 / 10期

关键词：

D O I：

10.1039/p19930001099

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Using Pseudomonas fluorescens lipase in vinyl acetate, the methyl 4,6-O-benzylidene-alpha-D-pyranosides 1 and 6-8 have been esterified with very high selectivity to afford the C-2 acetates 3 and 10-12, respectively. In contrast the methyl 4,6-O-benzylidene-beta-D-pyranosides 2 and 9 are acetylated under the same conditions to give the C-3 esters 5 and 13 with high/exquisite regioselectivity.

引用

页码：1099 / 1101

页数：3

共 6 条

[1] REGIOSELECTIVE ENZYMATIC ACETYLATION OF METHYL 4,6-O-BENZYLIDENE-ALPHA-D-GLUCOPYRANOSIDE AND 4,6-O-BENZYLIDENE-BETA-D-GLUCOPYRANOSIDE [J].