THE FORMATION AND METABOLISM OF N-HYDROXYMETHYL COMPOUNDS .7. IDENTIFICATION BY PROTON NMR OF N-(HYDROXYMETHYL)-N-METHYLFORMAMIDE AS THE MAJOR URINARY METABOLITE OF N,N-DIMETHYLFORMAMIDE IN MICE

被引：47

作者：

KESTELL, P

GILL, MH

THREADGILL, MD

GESCHER, A

HOWARTH, OW

CURZON, EH

机构：

[1] UNIV ASTON,CANC RES CAMPAIGN,EXPTL CHEMOTHERAPY GRP,BIRMINGHAM B4 7ET,W MIDLANDS,ENGLAND

[2] UNIV ASTON,MRC,MECHANISMS DRUG TOXIC GRP,BIRMINGHAM B4 7ET,W MIDLANDS,ENGLAND

[3] UNIV WARWICK,DEPT CHEM,COVENTRY CV4 7AL,W MIDLANDS,ENGLAND

来源：

LIFE SCIENCES | 1986年 / 38卷 / 08期

关键词：

D O I：

10.1016/0024-3205(86)90586-2

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：719 / 724

页数：6

共 42 条

[1] METABOLISM AND HEPATOTOXICITY OF N,N-DIMETHYLFORMAMIDE, N-HYDROXYMETHYL-N-METHYLFORMAMIDE, AND N-METHYLFORMAMIDE IN THE RAT
VANDENBULCKE, M
ROSSEEL, MT
WIJNANTS, P
BUYLAERT, W
BELPAIRE, FM
ARCHIVES OF TOXICOLOGY, 1994, 68 (05) : 291 - 295
[2] THE METABOLISM OF N,N-DIMETHYLFORMAMIDE (DMF) AND N-METHYLFORMAMIDE (NMF) IN MICE
KESTELL, P
GESCHER, A
BRITISH JOURNAL OF CANCER, 1985, 52 (03) : 416 - 417
[3] PROTON NMR SPECTRA OF THE N,N-DIMETHYLFORMAMIDE, N-METHYLFORMAMIDE, AND N,N-DIMETHYLACETAMIDE
KOWALEWSKI, VJ
DEKOWALEWSKI, DG
JOURNAL OF CHEMICAL PHYSICS, 1960, 32 (04): : 1272 - 1273
[4] THE FORMATION AND METABOLISM OF N-HYDROXYMETHYL COMPOUNDS .3. THE METABOLIC CONVERSION OF N-METHYL AND N,N-DIMETHYLBENZAMIDES TO N-HYDROXYMETHYL COMPOUNDS
ROSS, D
FARMER, PB
GESCHER, A
HICKMAN, JA
THREADGILL, MD
BIOCHEMICAL PHARMACOLOGY, 1983, 32 (11) : 1773 - 1781
[5] IDENTIFICATION OF N-ACETYL-S-(N-METHYLCARBAMOYL) CYSTEINE, A HUMAN METABOLITE OF N,N-DIMETHYLFORMAMIDE AND N-METHYLFORMAMIDE
MRAZ, J
TURECEK, F
JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1987, 414 (02): : 399 - 404
[6] THE ENTROPY OF FORMATION OF THE MERCURY SOLUTION INTERFACE IN N-METHYLFORMAMIDE AND N,N-DIMETHYLFORMAMIDE
BORKOWSKA, Z
STAFIEJ, J
JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 1984, 170 (1-2) : 89 - 98
[7] A comparison of micelle formation of ionic surfactants in formamide, in N-methylformamide and in N,N-dimethylformamide
Akhter, MS
Alawi, SM
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2003, 219 (1-3) : 281 - 290
[8] THE FORMATION AND METABOLISM OF N-HYDROXYMETHYL COMPOUNDS .4. CYTO-TOXICITY AND ANTI-TUMOR ACTIVITY OF N-HYDROXYMETHYLFORMAMIDE, A PUTATIVE METABOLITE OF N-METHYLFORMAMIDE (NSC-3051)
COOKSEY, PG
GATE, EN
GESCHER, A
HICKMAN, JA
LANGDON, SP
STEVENS, MFG
BIOCHEMICAL PHARMACOLOGY, 1983, 32 (20) : 3037 - 3043
[9] NMR SHIFT + DIFFUSION STUDY OF AQUEOUS MIXTURES OF FORMAMIDE N-METHYLFORMAMIDE + N,N-DIMETHYLFORMAMIDE
FRATIELL, A
MOLECULAR PHYSICS, 1964, 7 (06) : 565 - &
[10] THE GEOMETRY OF N-HYDROXYMETHYL COMPOUNDS .3. GEOMETRIES OF N-(HYDROXYMETHYL)-AMIDES RELATED TO REACTIVITIES
MALLAWAARACHCHI, W
SIMMONDS, RJ
PARRY, DE
ANTI-CANCER DRUG DESIGN, 1989, 4 (03): : 233 - 240

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