EXTRACTION PROCEDURES FOR THE HPLC DETERMINATION OF 5-FLUOROURACIL IN BIOLOGICAL SAMPLES

被引：7

作者：

DELNOZAL, MJ

BERNAL, JL

MARINERO, P

PAMPLIEGA, A

机构：

[1] Department of Analytical Chemistry, Faculty of Sciences, University of Valladolid, E-47005, Valladolid

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1994年 / 17卷 / 07期

关键词：

D O I：

10.1080/10826079408013184

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An extraction procedure was optimized for the reversed-phase high performance liquid chromatographic determination of 5-Fluorouracil in rabbit plasma, liver, kidney, lung and heart samples. The extraction conditions are adapted to each type of matrix in order to achieve high extraction yields (ca 90%) and interference-free chromatographic peaks.

引用

页码：1621 / 1636

页数：16

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