THE ROLE OF PHARMACOKINETICS IN THE DEVELOPMENT OF BIOTECHNOLOGICALLY DERIVED AGENTS

被引：16
作者：
WILLS, RJ
FERRAIOLO, BL
机构：
[1] Department of Drug Metabolism, R.W. Johnson Pharmaceutical Research Institute, Raritan, New Jersey
[2] R.W. Johnson Pharmaceutical Research Institute, Raritan, New Jersey, 08869
来源：
CLINICAL PHARMACOKINETICS | 1992年 / 23卷 / 06期
关键词：
D O I：
10.2165/00003088-199223060-00002
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
[No abstract available]
引用
收藏
页码：406 / 414
页数：9
相关论文
共 60 条
[31]  
LELCHUK R, 1985, IMMUNOLOGY, V56, P113
[32]   METABOLISM OF DIPEPTIDES AND THEIR CONSTITUENT AMINO-ACIDS BY LIVER, GUT, KIDNEY, AND MUSCLE [J].
LOCHS, H ;
WILLIAMS, PE ;
MORSE, EL ;
ABUMRAD, NN ;
ADIBI, SA .
AMERICAN JOURNAL OF PHYSIOLOGY, 1988, 254 (05) :E588-E594
[33]   RENAL FILTRATION, TRANSPORT, AND METABOLISM OF LOW-MOLECULAR-WEIGHT PROTEINS - REVIEW [J].
MAACK, T ;
JOHNSON, V ;
KAU, ST ;
FIGUEIREDO, J ;
SIGULEM, D .
KIDNEY INTERNATIONAL, 1979, 16 (03) :251-270
[34]   ELECTROPHORESIS AND DENSITOMETRY OF SERUM AND URINE IN THE INVESTIGATION AND SIGNIFICANCE OF MONOCLONAL IMMUNOGLOBULINS [J].
MACNAMARA, EM ;
WHICHER, JT .
ELECTROPHORESIS, 1990, 11 (05) :376-381
[35]   THE METABOLISM OF NEUROPEPTIDES - THE HYDROLYSIS OF PEPTIDES, INCLUDING ENKEPHALINS, TACHYKININS AND THEIR ANALOGS, BY ENDOPEPTIDASE-24-11 [J].
MATSAS, R ;
KENNY, AJ ;
TURNER, AJ .
BIOCHEMICAL JOURNAL, 1984, 223 (02) :433-440
[36]   DISAPPEARANCE RATES OF EXOGENOUS AND ENDOGENOUS ACTH FROM RAT PLASMA MEASURED BY BIOASSAY AND RADIOIMMUNOASSAY [J].
MATSUYAMA, H ;
RUHMANNW.A ;
JOHNSON, LR ;
NELSON, DH .
METABOLISM-CLINICAL AND EXPERIMENTAL, 1972, 21 (01) :30-+
[37]  
McMartin C, 1992, ADV DRUG RES, V22, P39, DOI [10.1016/b978-0-12-013322-2.50006-1, DOI 10.1016/B978-0-12-013322-2.50006-1]
[38]  
MOHLER MA, 1992, IN PRESS PROTEIN PHA
[39]   INTERSPECIES SCALING OF CLEARANCE AND VOLUME OF DISTRIBUTION DATA FOR 5 THERAPEUTIC PROTEINS [J].
MORDENTI, J ;
CHEN, SA ;
MOORE, JA ;
FERRAIOLO, BL ;
GREEN, JD .
PHARMACEUTICAL RESEARCH, 1991, 8 (11) :1351-1359
[40]   QUANTIFICATION OF RECOMBINANT INTERLEUKIN-2 IN HUMAN-SERUM BY A SPECIFIC IMMUNOBIOASSAY [J].
NADEAU, RW ;
OLDFIELD, NF ;
GARLAND, WA ;
LIBERATO, DJ .
ANALYTICAL CHEMISTRY, 1989, 61 (15) :1732-1736
123456