ALLOSTERIC MECHANISM OF ENHANCER ACTION

被引：6
|
作者：
STUDITSKY, VM
机构：
[1] W.A. Engelhardt Institute of Molecular Biology, Academy of Sciences, the USSR, 117984 Moscow, B-334
来源：
FEBS LETTERS | 1991年 / 280卷 / 01期
关键词：
EUKARYOTIC ENHANCER; ALLOSTERIC ACTION IN TRANS; ENHANCER AND PROMOTER ELEMENT; STABLE INITIATION COMPLEX;
D O I：
10.1016/0014-5793(91)80191-5
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A recurrent theme in molecular biology is 'action at a distance' along DNA. Why can some regulatory DNA sequences (enhancers) work at a great distance from the target of regulation? As one possible solution to this question we shall consider an allosteric mechanism of enhancer action focused on eukaryotic transcriptional enhancers.
引用
收藏
页码：5 / 7
页数：3
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