PROBING PROTEIN CONFORMATION BY A COMBINATION OF ELECTROSPRAY MASS-SPECTROMETRY AND MOLECULAR MODELING

被引：17

作者：

BROWN, C ^{[1
]}

CAMILLERI, P ^{[1
]}

HASKINS, NJ ^{[1
]}

SAUNDERS, M ^{[1
]}

机构：

[1] SMITHKLINE BEECHAM PHARMACEUT,WELWYN GARDEN CIT AL6 9AR,HERTS,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1992年 / 10期

关键词：

D O I：

10.1039/c39920000761

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Electrospray-ionisation mass spectrometry and molecular modelling have been used to probe two conformations of tuna cytochrome c; the number of protons which could be exchanged by deuterons was in remarkable agreement with that calculated using an algorithm for the determination of solvent-accessible surface.

引用

页码：761 / 764

页数：4

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