Biomarkers in Acute Decompensated Heart Failure

被引：0

作者：

Rosenbaum, Andrew N. ^{[1
]}

Miller, Wayne L. ^{[2
]}

机构：

[1] Mayo Clin, Dept Med, Rochester, MN 55905 USA

[2] Mayo Clin, Div Cardiovasc Dis, Rochester, MN 55905 USA

来源：

CLINICAL MEDICINE INSIGHTS-THERAPEUTICS | 2015年 / 7卷

关键词：

acute decompensated heart failure; NT-proBNP; diagnosis; biomarkers;

D O I：

10.4137/CMT.S18476

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Acute decompensated heart failure (ADHF) is a prominent condition whose frequency is increasing, especially in the context of an aging population. The ability to discern the cause of undifferentiated dyspnea in acute presentations is an increasing struggle. In this review, we seek to explore the various biomarkers that have been studied for the diagnosis of ADHF and their respective clinical utilities as the most recent data would suggest. Natriuretic peptides, galectin-3, soluble ST2, adrenomedullin, cardiac troponin-T, neutrophil gelatinase-associated lipocalin, and copeptin are reviewed. Of these biomarkers, natriuretic peptides are the most thoroughly evaluated and show the most promise for diagnosis or exclusion of acute heart failure, though other biomarkers can add significant utility in the form of prognostication.

引用

页码：33 / 42

页数：10

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