SEGREGATION ANALYSIS OF 4 TRANSLOCATIONS, T(2-18), T(3-15), T(5-7), AND T(10-12), BY SPERM CHROMOSOME-STUDIES AND A REVIEW OF THE LITERATURE

被引：59

作者：

ESTOP, AM

VANKIRK, V

CIEPLY, K

机构：

[1] W PENN HOSP,DIV MED GENET,PITTSBURGH,PA

[2] UNIV PITTSBURGH,DEPT HUMAN GENET,PITTSBURGH,PA 15260

来源：

CYTOGENETICS AND CELL GENETICS | 1995年 / 70卷 / 1-2期

关键词：

D O I：

10.1159/000133997

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

We examined the meiotic segregation patterns of 444 sperm cells belonging to four reciprocal translocation carriers, t(2;18)(p21;q11.2), t(3;15)(q26.2; q26.1), t(5;7)(q13;p15.1), and t(10;12)(q26.1;p13.3). For the t(2;18) carrier, the frequencies of alternate, adjacent-1, adjacent-2, and 3:1 segregations were 41.9%, 35.2%, 14.4%, and 8.4%, respectively. For the t(3;15) carrier, the segregation pattern was 48% alternate, 36% adjacent-1, 12% adjacent-2, 2% 3:1, and 2% 4:0. One cell was the result of a 4:0 segregation. For the t(5;7) heterozygote, the corresponding segregation frequencies were

引用

页码：80 / 87

页数：8

共 24 条

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