LACK OF ASSOCIATION BETWEEN DOPAMINE-D1 AND DOPAMINE-D2 RECEPTOR GENES AND BIPOLAR AFFECTIVE-DISORDER

被引：0

作者：

NOTHEN, MM

ERDMANN, J

KORNER, J

LANCZIK, M

FRITZE, J

FIMMERS, R

GRANDY, DK

ODOWD, B

PROPPING, P

机构：

[1] UNIV BONN,INST HUMAN GENET,DEPT PSYCHIAT,WILHELMSTR 31,W-5300 BONN 1,GERMANY

[2] UNIV BONN,INST MED STAT,W-5300 BONN 1,GERMANY

[3] UNIV WURZBURG,DEPT PSYCHIAT,W-8700 WURZBURG,GERMANY

[4] OREGON HLTH SCI UNIV,VOLLUM INST,PORTLAND,OR 97201

[5] UNIV TORONTO,DEPT PHARMACOL,TORONTO M5S 1A1,ONTARIO,CANADA

来源：

AMERICAN JOURNAL OF PSYCHIATRY | 1992年 / 149卷 / 02期

关键词：

D O I：

暂无

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

Fifty-six patients with bipolar affective disorder and 69 healthy control subjects were tested for association of restriction fragment length polymorphism alleles at the dopamine D1 and D2 receptor loci. No significant associations were found; thus, the hypothesis that a single mutant form of either receptor gene is responsible for the phenotype of patients with bipolar affective disorder was not supported.

引用

页码：199 / 201

页数：3

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