HISTAMINE LEVEL AND TRANSGLUTAMINASE ACTIVITY MAY PROVIDE INDICATION OF THE DEVELOPMENT OF SPONTANEOUS MAMMARY-TUMOR IN C3H MICE

被引：0
作者：
MASLINSKI, C
KIERSKA, D
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来源：
AGENTS AND ACTIONS | 1992年
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O6 [化学];
学科分类号：
0703 ;
摘要：
Histamine (HA) concentrations and HA metabolizing enzyme activities were measured in macroscopically unchanged mammary glands and in tumor tissue of C3H mice carrying spontaneous mammary tumor as well as in mammary glands of control subjects matched for age. The great fall in HA level and the enzyme activities in tumor tissue was confirmed. In host mammary glands which showed no current evidence of neoplasm, consistently lower than normal HA concentrations and elevated transglutaminase (TG) activity were found. It is suggested, therefore, that HA level and TG activity may provide an early indication of the development of spontaneous mammary tumor.
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页码：C384 / C386
页数：3
相关论文
共 9 条
[1]  
BARTHOLEYNS J, 1984, CANCER RES, V44, P639
[2]   ROLE OF HISTAMINE IN TUMOR-DEVELOPMENT [J].
BARTHOLEYNS, J ;
FOZARD, JR .
TRENDS IN PHARMACOLOGICAL SCIENCES, 1985, 6 (03) :123-125
[3]   ENZYMATIC HISTAMINE CATABOLISM IN VERTEBRATE ONTOGENESIS - A COMPARATIVE-STUDY [J].
FOGEL, WA .
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 1988, 89 (02) :355-360
[4]   TRANSGLUTAMINASES [J].
FOLK, JE .
ANNUAL REVIEW OF BIOCHEMISTRY, 1980, 49 :517-531
[5]   SELECTIVE INCREASED TISSUE HISTAMINE LEVELS IN TUMOR-BEARING RODENTS [J].
FRAY, A ;
LESPINATS, G ;
SCHEINMANN, P ;
SALOMON, JC ;
PAUPE, J ;
CANU, P ;
VILLET, R ;
BURTIN, C .
AGENTS AND ACTIONS, 1983, 13 (2-3) :230-233
[6]   CHANGES IN HISTAMINE SYNTHESIS, TISSUE CONTENT AND CATABOLISM IN HUMAN-BREAST CANCER [J].
GARCIACABALLERO, M ;
NEUGEBAUER, E ;
RODRIGUEZ, F ;
DECASTRO, IN ;
HEREDIA, A ;
OOSTING, E ;
THORBECK, CV .
AGENTS AND ACTIONS, 1989, 27 (1-2) :227-231
[7]   FILTER PAPER ASSAY FOR TRANSAMIDATING ENZYMES USING RADIOACTIVE AMINE SUBSTRATES [J].
LORAND, L ;
COOPERST.L ;
CAMPBELL.LK .
ANALYTICAL BIOCHEMISTRY, 1972, 50 (02) :623-&
[8]   HISTAMINE IN C3H/W MICE CARRYING SPONTANEOUS TUMORS OF THE MAMMARY-GLAND [J].
MASLINSKI, C ;
KIERSKA, D .
AGENTS AND ACTIONS, 1991, 33 (1-2) :192-194
[9]   INCREASE IN HISTIDINE-DECARBOXYLASE ACTIVITY IN MOUSE SKIN AFTER APPLICATION OF THE TUMOR PROMOTER TETRADECANOYLPHORBOL ACETATE [J].
WATANABE, T ;
TAGUCHI, Y ;
SASAKI, K ;
TSUYAMA, K ;
KITAMURA, Y .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1981, 100 (01) :427-432
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