VINYL RADICAL CYCLIZATIONS - SYNTHESIS OF SUBSTITUTED BICYCLOOCTANOLS

被引：21

作者：

BERKOWITZ, WF

WILSON, PJ

机构：

[1] Department of Chemistry and Biochemistry, City University of New York at Queens College, Flushing

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 09期

关键词：

D O I：

10.1021/jo00009a032

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The preparation and free-radical bicyclic ring closure of 4-(2-bromo-2-propen-1-yl)cyclohexene 7 is described. The bicyclo[3.2.1] and -[2.2.2] alcohols 9 and 10 arising, respectively, from 5-exo and 6-endo (or 6-exo) modes of cyclization of a vinyl radical were isolated in a 1:1 ratio. Factors affecting the regiochemical outcome were investigated.

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页码：3097 / 3102

页数：6

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