Percutaneous treatment in acute coronary syndromes

被引：3

作者：

Alegria-Barrero, Eduardo ^{[1
]}

Moreno, Raul ^{[2
]}

机构：

[1] Royal Brompton Hosp, Intervent Cardiol, Sydney St, London SW3 6NP, England

[2] Laz Paz Univ Hosp, Intervent Cardiol Unit, Madrid 28046, Spain

来源：

WORLD JOURNAL OF CARDIOLOGY | 2011年 / 3卷 / 10期

关键词：

Coronary revascularization; Acute coronary syndromes; Stent; ST-elevation mymyocardial infarction; Non-ST-elevation mymyocardial infarction;

D O I：

10.4330/wjc.v3.i10.315

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Both ST-segment elevation myocardial infraction and non-ST-segment elevation mymyocardial infarction and non-ST-segment elevation acute coronary syndromes (ACS) are the result of an acute thrombotic lesion obstructing blood flow in the coronary vasculature. Percutaneous treatment has shown to improve clinical outcome in this clinical setting by resolving coronary obstruction with difffferent devices directed to restore coronary blood flow. In comparison with balloon alone angioplasty, implantation of bare metal stents reduced the rate of restenosis and cardiac events, but high rates of restenosis remained, leading to further investigations to develop drug- eluting stents with difffferent pharmacological coatings that reduced restenosis rates and clinical events. In this review, we discuss the current treatment of ACS, reviewing recent randomized clinical trials and advances in medical treatment, including new antiplatelet agents and recent guideline recommmmendations. (C) 2011 Baishideng. All rights reserved.

引用

页码：315 / 321

页数：7

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