NONSTEROIDAL ANTIINFLAMMATORY DRUGS - GASTRODUODENAL INJURY AND BEYOND

被引:5
|
作者
BERNSDORFF, KR
AGRAWAL, RM
BRODMERKEL, GJ
机构
[1] Allegheny General Hospital Pittsburgh, Allegheny Campus. Medical College of Pennsylvania, Hahnemann University, Philadelphia, PA
关键词
NONSTEROIDAL ANTIINFLAMMATORY DRUGS; GASTRODUODENAL MUCOSAL INJURY; PROSTAGLANDINS; NSAID ENTEROPATHY; COMPLICATIONS; COLONIC NEOPLASMS;
D O I
10.1159/000171506
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
The use of nonsteroidal anti-inflammatory drugs (NSAIDs) is extensive, and the upper gastrointestinal (GI) side effects of these drugs have been well recognized. Although much attention has been focused on gastroduodenal ulceration and attendant complications, it is becoming more apparent that NSAIDs exert potentially important effects on the small bowel and colon. The widespread effects of NSAIDs on the GI system, including theories of pathogenesis, will be presented here.
引用
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页码:251 / 266
页数:16
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