Review of clinical studies of Polygonum multiflorum Thunb. and its isolated bioactive compounds

被引：98
作者：
Bounda, Guy-Armel [1 ]
Yu, Feng [1 ,2 ]
机构：
[1] China Pharmaceut Univ, Dept Clin Pharm, Nanjing 210009, Jiangsu, Peoples R China
[2] China Pharmaceut Univ, Minist Educ, Key Lab Drug Qual Control & Pharmacovigilance, Nanjing 210009, Jiangsu, Peoples R China
来源：
PHARMACOGNOSY RESEARCH | 2015年 / 7卷 / 03期
关键词：
Clinical pharmacokinetics; clinical studies; herbal hepatotoxicity; Polygonum multiflorum Thunb; therapeutic assessment;
D O I：
10.4103/0974-8490.157957
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Polygonum multiflorum Thunb. (PMT), officially listed in the Chinese Pharmacopoeia, is one of the most popular perennial Chinese traditional medicines known as He shou wu in China and East Asia, and as Fo-ti in North America. Mounting pharmacological studies have stressed out its key benefice for the treatment of various diseases and medical conditions such as liver injury, cancer, diabetes, alopecia, atherosclerosis, and neurodegenerative diseases as well. International databases such as PubMed/Medline, Science citation Index and Google Scholar were searched for clinical studies recently published on P. multiflorum. Various clinical studies published articles were retrieved, providing information relevant to pharmacokinetics-pharmacodynamics analysis, sleep disorders, dyslipidemia treatment, and neurodegenerative diseases. This review is an effort to update the clinical picture of investigations ever carried on PMT and/or its isolated bio-compounds and to enlighten its therapeutic assessment.
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收藏
页码：225 / 236
页数：12
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