MOLECULAR-BASIS OF HEMOPHILIA-B - A DEFECTIVE ENZYME DUE TO AN UNPROCESSED PROPEPTIDE IS CAUSED BY A POINT MUTATION IN THE FACTOR-IX PRECURSOR

被引：122

作者：

DIUGUID, DL ^{[1
]}

RABIET, MJ ^{[1
]}

FURIE, BC ^{[1
]}

LIEBMAN, HA ^{[1
]}

FURIE, B ^{[1
]}

机构：

[1] TUFTS UNIV,SCH MED,BOSTON,MA 02111

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1986年 / 83卷 / 16期

关键词：

D O I：

10.1073/pnas.83.16.5803

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：5803 / 5807

页数：5

共 39 条

[11]

BOROWSKI M, 1985, J BIOL CHEM, V260, P9258

[12]

BOROWSKI M, 1986, J BIOL CHEM, V261, P1624

[13] CIRCULATING VARIANT OF HUMAN PROALBUMIN [J].

BRENNAN, SO ;

CARRELL, RW .

NATURE, 1978, 274 (5674) :908-909

[14] MOLECULAR-CLONING OF THE GENE FOR HUMAN ANTI-HEMOPHILIC FACTOR-IX [J].

CHOO, KH ;

GOULD, KG ;

REES, DJG ;

BROWNLEE, GG .

NATURE, 1982, 299 (5879) :178-180

[15]

DAVIS LM, 1984, BLOOD S, V64, P262

[16] CHARACTERIZATION OF PROTEIN S, A GAMMA-CARBOXYGLUTAMIC ACID CONTAINING PROTEIN FROM BOVINE AND HUMAN-PLASMA [J].

DISCIPIO, RG ;

DAVIE, EW .

BIOCHEMISTRY, 1979, 18 (05) :899-904

[17]

DIUGUID DL, 1985, BLOOD S, V66, P332

[18]

GIANNELLI F, 1983, NATURE, V303, P181, DOI 10.1038/303181a0

[19] QUANTITATIVE-DETERMINATION OF GAMMA-CARBOXYGLUTAMIC ACID IN PROTEINS [J].

HAUSCHKA, PV .

ANALYTICAL BIOCHEMISTRY, 1977, 80 (01) :212-223

[20]

HEWICK RM, 1981, J BIOL CHEM, V256, P7990

← 1 2 3 4 →