EFFECTS OF PROPOFOL-SUFENTANIL ASSOCIATION ON SOMATOSENSORY-EVOKED POTENTIALS DURING SPINE SURGERY

被引：9

作者：

BORRISSOV, B ^{[1
]}

LANGERON, O ^{[1
]}

LILLE, F ^{[1
]}

GOMOLA, A ^{[1
]}

SAILLANT, G ^{[1
]}

RIOU, B ^{[1
]}

VIARS, P ^{[1
]}

机构：

[1] GRP HOSP PITIE SALPETRIERE,DEPT ANESTHESIE REANIMAT,F-75653 PARIS 13,FRANCE

来源：

ANNALES FRANCAISES D ANESTHESIE ET DE REANIMATION | 1995年 / 14卷 / 04期

关键词：

PROPOFOL; SUFENTANIL; SOMATOSENSORY EVOKED POTENTIALS; SPINE; SURGERY;

D O I：

10.1016/S0750-7658(05)80598-2

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Objectives: Most anaesthetics depress cortical somatosensory evoked potentials (CSEPs). However, the modification of CSEPs during total intravenous anaesthesia using propofol remaining still unknown, justified this trial. Type of study: Open, prospective, clinical study. Methods: Nine consecutive patients requiring CSEPs monitoring for spine surgery, were studied. Anaesthesia was induced with propofol (25 mg . kg(-1) then 10 mg . kg(-1). h(-1)) and sufentanil (0.50 mu g . kg(-1) then 0.25 mu g . kg(-1). h(-1)). Maximum positive (P40) and negative (N50) waweform latencies, and the peak to peak amplitude of CSEPs (posterior tibial nerve stimulation, cortical recording), were recorded before induction, 30 min, 1 and 2 h after induction, and at the end of surgery. Data are means +/- SD. Results: Duration of anaesthesia was 260 +/- 73 min. Propofol induced significant lengthening of CSEPS (P40: from 37 +/- 10 up to 41 +/- 11 ms; N50: from 45 +/- 11 up to 51 +/- 14 ms), and a significant decrease in amplitude (from 1.9 +/- 0.9 down to 0.8 +/- 0.4 mu V), but these changes were stable from 30 min after the induction to the end of spine surgery. A motor response was obtained 29 +/- 14 min after the end of anaesthetic administration. Conclusions: Total intravenous anaesthesia with propofol and sufentanil induces a small but stable lengthening of CSEPs latency and a stable decrease of its amplitude, which enable an appropriate monitoring of CSEPs during spine surgery.

引用

页码：326 / 330

页数：5