A CASE OF SPINAL-CORD COMPRESSION BY EXTRAMEDULLARY HEMATOPOIESIS IN A THALASSEMIC PATIENT - A PUTATIVE ROLE FOR HYDROXYUREA

被引：0
作者：
KONSTANTOPOULOS, K [1 ]
VAGIOPOULOS, G [1 ]
KANTOUNI, R [1 ]
LYMPERI, S [1 ]
PATRIARCHEAS, G [1 ]
GEORGAKOPOULOS, D [1 ]
FESSAS, P [1 ]
机构：
[1] UNIV ATHENS,LAIKON HOSP,DEPT MED 1,ATHENS,GREECE
来源：
HAEMATOLOGICA | 1992年 / 77卷 / 04期
关键词：
THALASSEMIA; EXTRAMEDULLARY HEMATOPOIESIS; HYDROXYUREA;
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We report a case of homozygous beta thalassaemia who developed chronic paraparesis due to spinal cord compression by paravertebral extramedullary masses. Our patient was successfully treated with hupertransfusion and hydroxyurea. This drug in addition to its well-known cytostatic effects, may be a good alternative in conditions analogous to our case. This action of hydroxyurea can also be attributed to its favourable effect on foetal haemoglobin production.
引用
收藏
页码：352 / 354
页数：3
相关论文
共 50 条
  • [21] Extramedullary hematopoiesis causing spinal cord compression in polycythemia vera: A case report and literature review
    Cailleteau, Axel
    Agbetsivi, Komivi
    Guimas, Valentine
    Supiot, Stephane
    Ollivier, Luc
    CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY, 2023, 38 : 43 - 46
  • [22] Epidural Spinal Cord Compression due to Extramedullary Hematopoiesis: Systematic Review of the Literature with an Illustrative Case
    Lam, Nicholas G.
    Ahmadpour, Arjang
    Gimelfarb, Alla
    Nanda, Ranjeev
    Ares, William J.
    WORLD NEUROSURGERY, 2025, 193 : 119 - 130
  • [23] Spinal cord compression due to extramedullary hematopoiesis in a patient with E-beta-thalassemia managed without radiation or surgery
    La, Van T.
    Diatte, Michael
    Gaston, Johnathan
    Dick, Dallas
    Sweiss, Raed
    Pakbaz, Zahra
    JOURNAL OF COMMUNITY HOSPITAL INTERNAL MEDICINE PERSPECTIVES, 2018, 8 (04): : 246 - 249
  • [24] Management of Spinal Cord Compression Caused by Extramedullary Hematopoiesis in Beta-thalassemia
    Moncef, Berhouma
    Hafedh, Jemel
    INTERNAL MEDICINE, 2008, 47 (12) : 1125 - 1128
  • [25] Painful spinal cord compression as a complication of extramedullary Hematopoiesis associated with β-thalassemia intermedia
    Goerner, Martin
    Gerull, Sabine
    Schaefer, Erhard
    Just, Marianne
    Sure, Martin
    Hirnle, Peter
    STRAHLENTHERAPIE UND ONKOLOGIE, 2008, 184 (04) : 224 - 226
  • [26] Extramedullary hematopoiesis presenting with thoracic spinal cord compression in a young adult with thalassemia major: A case report
    Gupta, Prasheelkumar
    Shaikh, Salman
    Goyal, Richa
    Gupta, Deepak
    JOURNAL OF PEDIATRIC NEUROSCIENCES, 2021, 16 (04) : 303 - 306
  • [27] Spinal cord compression due to extramedullary hematopoiesis in beta-thalassemia intermedia
    Munn, RK
    Kramer, CA
    Arnold, SM
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1998, 42 (03): : 607 - 609
  • [28] Extramedullary hematopoiesis causing spinal cord compression with excellent durable response after radiation therapy: Case report and review of the literature
    Fontanesi, James
    Margolis, Harold
    Fontanesi, Giovanni R.
    JOURNAL OF FAMILY MEDICINE AND PRIMARY CARE, 2020, 9 (07) : 3741 - 3744
  • [29] Progressive Spinal Cord Compression Due to Epidural Extramedullary Hematopoiesis in Thalassemia Intermedia A Case Report and Literature Review
    Ghieda, U.
    Elshimy, M.
    El Beltagi, A. H.
    NEURORADIOLOGY JOURNAL, 2013, 26 (01) : 111 - 117
  • [30] Renal splenic heterotopia with extramedullary hematopoiesis in a thalassemic patient, simulating renal neoplasm: A case report
    Hiradfar, Mehran
    Zabolinejadin, Nona
    Banihashem, Abdolla
    Kajbafzadeh, Abdol-Mohammad
    JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2007, 29 (03) : 195 - 197
12345